DCUN1D4

DCUN1D4

Identifiers

DCUN1D4, defective in cullin neddylation 1 domain containing 4, DCNL4

External IDs

OMIM: 612977; MGI: 2140972; GeneCards: DCUN1D4

Gene location (Human)

Chr.	Chromosome 4 (human)

Band	4q12	Start	51,843,000 bp
Band	4q12	End	51,916,837 bp

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)

Band	5\|5 C3.3	Start	73,638,343 bp
Band	5\|5 C3.3	End	73,718,137 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

Achilles tendon

epithelium of colon

germinal epithelium

testicle

left ovary

right ovary

tail of epididymis

popliteal artery

gastric mucosa

tibial arteries

Top expressed in

spermatid

visual cortex

lateral hypothalamus

amygdala

primary visual cortex

superior frontal gyrus

ventromedial nucleus

zygote

genital tubercle

yolk sac

More reference expression data


More reference expression data

Gene ontology
Molecular function	cullin family protein binding ubiquitin-like protein binding protein binding ubiquitin conjugating enzyme binding molecular function
Cellular component	nucleus ubiquitin ligase complex
Biological process	protein neddylation positive regulation of ubiquitin-protein transferase activity biological process
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


23142


100737


ENSG00000109184


ENSMUSG00000051674


Q92564


Q8CCA0

RefSeq (mRNA)


NM_001040402 NM_001287755 NM_001287757 NM_015115


NM_001190733 NM_001190734 NM_178896

RefSeq (protein)


NP_001035492 NP_001274684 NP_001274686 NP_055930


NP_001177662 NP_001177663 NP_849227

Location (UCSC)

Chr 4: 51.84 – 51.92 Mb

Chr 5: 73.64 – 73.72 Mb

PubMed search

View/Edit Human

View/Edit Mouse

DCN1-like protein 4 is a protein that in humans is encoded by the DCUN1D4 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000109184 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051674 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, Hofmann K, Hyman AA, Bowerman B, Peter M (Jun 2005). "The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae". Nature. 435 (7046): 1257–61. Bibcode:2005Natur.435.1257K. doi:10.1038/nature03662. PMID 15988528. S2CID 4328225.
↑ "Entrez Gene: DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)".

Further reading

Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Hartley JL, Temple GF, Brasch MA (2001). "DNA Cloning Using In Vitro Site-Specific Recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to Biology: A Functional Genomics Pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.

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