Darrion Nguyen

Darrion Nguyen
Nguyen in 2023
Born (1994-10-20) October 20, 1994 (age 32)
Houston, Texas, U.S.
EducationKlein Forest High School University of Texas at Austin University of the Arts London
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Last updated: December 10 2025

Darrion Nguyen (born October 20, 1994) is an Asian American science communicator, fashion designer, and digital creator. He is best known for portraying Dr. Ion on the Ryan's World YouTube channel and for his educational science content on social media.

Early life and education

Darrion Nguyen was born on October 20, 1994, to Dung and Thi Nguyen and is of Vietnamese descent. Nguyen was raised in Houston, Texas. At age 11, his father was killed during a robbery at the family's convenience store. Following the incident, Nguyen fled to seek help and upon returning, found his father had died. Nguyen later graduated from Klein Forest High School before earning a Bachelor of Science and Arts in Biochemistry and a Bachelor of Arts in Theatre & Dance from the University of Texas at Austin in 2017.

Nguyen later returned to school to study fashion design, completing an Associate of Applied Science in Fashion Design. Nguyen was recently accepted into master's programs in fashion design at the University of the Arts London and Parsons Paris.

Science communication

While working as a research technician in 2018, Nguyen began publishing educational science videos to Instagram and TikTok. His videos involve the use of popular audios to personify and dramatize specific biochemistry topics. His audience grew substantially during the COVID-19 pandemic when he focused on COVID-19 vaccine education and combating misinformation.

In 2021, Nguyen was an invited speaker at TEDxSalisbury, where he discussed the significance of educational yet relatable online content and how it can be leveraged to make science easily accessible.

In 2022, Nguyen partnered with Pfizer and Real Chemistry to produce a video series called I Heard it on The Internet aimed at debunking COVID-19 misinformation and rumors. The series has been named a finalist for the 2023 Shorty Award in the category of Best Video Series and Pharma & Healthcare.

In February 2023, Nguyen presented a second TEDx Talk at TEDxUTAustin titled “Reaching Objectives through Improv,” where he discussed the significance of integrating key principles of improvisational theatre into daily routines and interactions.

Nguyen portrays Dr. Ion on the Ryan's World YouTube channel.

Fashion career

Nguyen's winning garment for MFAH's Fashion Fusion X: "Frida: The Making of an Icon" Runway Show

In March 2024, Nguyen was featured in a Lone Star Live SXSW fashion article covering street style at the festival. The article included a photograph of Nguyen wearing a self-made outfit constructed from upcycled clothing and identified him as a fashion student attending a Tide-sponsored event during SXSW.

In June 2025, Nguyen won first place in the Comic Couture Competition at Comicpalooza in Houston, Texas, for an original design inspired by Aang from the animated television series Avatar: The Last Airbender.

In September 2025, Nguyen won first place in the ACE NextGen x Macy's Sustainable Fashion Project for his sustainable garment, Forecast: Reuse.

Later that year, he competed in his fourth fashion design competition, the Pierre Cardin Young Designers Award (PCYDA), where he won the national Best Creativity Prize.

On January 30th, 2026, Nguyen competed in the Museum of Fine Arts, Houston's fashion competition, Fashion Fusion X: "Frida: The Making of an Icon" Runway Show. He competed in the Reimagine: Reinvent Menswear category, in which designers transformed traditionally feminine garments into menswear. Nguyen was the student winner in this category.

Recently, Nguyen was named a recipient of the Fashion Scholarship Fund scholarship.

Television

Nguyen has appeared as himself on the television programs Kal Penn Approves This Message (2020) and Space Greed (2021), which aired on Curiosity Stream.

In December 2024, he competed in the first season of the reality competition series Beast Games, created by MrBeast, as contestant 878. He advanced to the top 250 out of an initial field of 2,000 contestants.

Awards and nominations

Year Award Category Work Result
2023 Shorty Award Video Series I Heard it on The Internet Video Content Series Finalist
Pharma & Healthcare I Heard it on The Internet Video Content Series Finalist
2025 Comicpalooza Comic Couture Fashion Design "Air Nomad" First Place
2025 ACE NextGen x Macy's Sustainable Fashion Project Fashion Design "Forecast: Reuse: First Place
2025 Pierre Cardin Young Designers Award (PCYDA) Fashion Design Best Creativity
2026 MFAH's Fashion Fusion X: "Frida: The Making of an Icon" Fashion Design "Blossoms in Maroon" Student Winner
2026 Fashion Scholarship Fund Fashion Design Recipient

Research

In 2024, the Office of Research Integrity (ORI) found that Nguyen had engaged in research misconduct involving the falsification and fabrication of experimental data in federally funded research conducted in 2018. Nguyen publicly acknowledged the findings, and accepted full responsibility, stating that his actions stemmed from fear of his principal investigator, pressure to meet laboratory expectations, and personal struggles in the laboratory, while emphasizing that these circumstances did not excuse his conduct.

References

  1. 1 2 3 "Articles | HCC Fashion Design students garner honors at Pierre Cardin Young Designers Award competition | Houston City College (HCC) | Local Focus. Global Reach". www.hccs.edu. Retrieved March 10, 2026.
  2. ↑ "Into the Newsroom: Teaching Through TikToks – Yale Scientific Magazine". www.yalescientific.org. Retrieved March 1, 2023.
  3. ↑ "Darrion Nguyen". IMDb. Retrieved March 1, 2023.
  4. ↑ KILDAY, ANNE MARIE (June 16, 2006). "Houston grocery store owner slain in robbery by two gunmen". Chron. Retrieved June 22, 2026.
  5. ↑ Bual, Hiezle (October 20, 2021). "Introducing The Tiktok-Famous Vietnamese-American 'Bill Nye Of Millennials'". Vietcetera. Retrieved March 1, 2023.
  6. ↑ Meeks, Flori (June 4, 2013). "Motivation matters most to Klein Forest student". Chron. Retrieved March 1, 2023.
  7. ↑ Stories, Local (February 8, 2022). "Meet Darrion Nguyen – Voyage Houston Magazine | Houston City Guide". voyagehouston.com. Retrieved March 1, 2023.
  8. 1 2 3 "Articles | Fashion Fusion celebrates 10 years with a stunning, iconic tribute to Frida Kahlo | Houston City College (HCC) | Local Focus. Global Reach". www.hccs.edu. Retrieved March 10, 2026.
  9. ↑ "Instagram". www.instagram.com. Retrieved June 22, 2026.
  10. ↑ "Meet Darrion Nguyen, the Bill Nye of millennials". Inverse. September 2020. Retrieved March 1, 2023.
  11. ↑ "Scientists on Social Media: Darrion Nguyen (aka lab_shenanigans)". eLife. September 3, 2021. Retrieved March 1, 2023.
  12. ↑ Lemonick, Sam (February 21, 2020). "Chemists are finding their place on TikTok". C&EN. Retrieved March 1, 2023.
  13. ↑ Swift, Jocelyn E.; Lovett, Brian; Koltermann, Christine E.; Beck, Chelsey L.; Kasson, Matt T. (2020). "From Hashtag to High School: How Viral Tweets Are Inspiring Young Scientists To Embrace STEM". Journal of Microbiology & Biology Education. 21 (3): 21.3.67. doi:10.1128/jmbe.v21i3.2133. ISSN 1935-7877. PMC 7669281. PMID 33294094.
  14. ↑ Currin, Grant. "These Videos Could Boost COVID Vaccination Rates". Scientific American. Retrieved March 1, 2023.
  15. ↑ "Social media meets science in 'Lab Shenanigans' with TikTok-famous researcher — and sometimes Pfizer partner". Endpoints News. Retrieved March 1, 2023.
  16. ↑ University, Salisbury (May 14, 2021). "SU TEDx Event 'The University Experience' Highlights Campus Voices". Salisbury University. Retrieved April 4, 2023.
  17. ↑ ""I Heard it on the Internet" Explainer Video Content Series - The Shorty Awards". shortyawards.com. Retrieved April 14, 2023.
  18. ↑ "A Reflection - TEDxUTAustin 2023: "How & Why"". TEDxUTAustin. March 21, 2023. Retrieved February 27, 2024.
  19. ↑ Ugrinow, Taylor (March 11, 2024). "Fashion trends and what to wear at Austin's SXSW 2024". lonestarlive. Retrieved July 5, 2026.
  20. ↑ "Instagram". www.instagram.com. Retrieved July 3, 2026.
  21. ↑ "Instagram". www.instagram.com. Retrieved July 5, 2026.
  22. ↑ "2026 Named Scholarship Programs". Fashion Scholarship Fund. Retrieved July 9, 2026.
  23. ↑ "Darrion Nguyen". www.imdb.com. Retrieved July 5, 2026.
  24. ↑ MrBeast 2 (February 12, 2025). Beast Games | Episode 2 (Full Episode). Retrieved June 22, 2026 – via YouTube.{{cite AV media}}: CS1 maint: numeric names: authors list (link)
  25. ↑ "Case Summary: Nguyen, Darrion".
  26. ↑ "'Lab shenanigans': TikTok influencer faked data, feds say". May 23, 2024.