Dinitolmide

Dinitolmide
Names
Preferred IUPAC name
2-Methyl-3,5-dinitrobenzamide
Other names
3,5-Dinitro-o-toluamide
Zoalene
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.005.189 Edit this at Wikidata
UNII
  • InChI=1S/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12) checkY
    Key: ZEFNOZRLAWVAQF-UHFFFAOYSA-N checkY
  • InChI=1/C8H7N3O5/c1-4-6(8(9)12)2-5(10(13)14)3-7(4)11(15)16/h2-3H,1H3,(H2,9,12)
    Key: ZEFNOZRLAWVAQF-UHFFFAOYAL
  • O=[N+]([O-])c1cc(cc(C(=O)N)c1C)[N+]([O-])=O
Properties
C8H7N3O5
Molar mass 225.16 g/mol
Melting point 177 °C; 351 °F; 450 K
Pharmacology
QP51AX12 (WHO)
Hazards
Flash point noncombustible
NIOSH (US health exposure limits):
PEL (Permissible)
 none
REL (Recommended)
 TWA 5 mg/m3
IDLH (Immediate danger)
 N.D.
Related compounds
Related compounds
 3,5-Dinitrobenzoic acid
o-Toluic acid
Trinitrotoluene
2,4-Dinitrotoluene
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dinitolmide (or zoalene) is a fodder additive for poultry, used to prevent coccidiosis infections. It is sold under trade names such as Coccidine A, Coccidot, and Zoamix.

Dinitolmide is usually added to feed in doses of 125 ppm (preventive) or 250 ppm (curative). It is a broad-spectrum anticoccidial drug, preventing seven main strains of Eimeria coccidium. It leaves no residues in tissues.[citation needed] It can be also used to prevent coccidiosis of domestic rabbits.

References

  1. 1 2 3 4 5 "#0230". NIOSH Pocket Guide to Chemical Hazards. National Institute for Occupational Safety and Health.
  2. 1 2 Gerhold, R. W.; Fuller, A. L.; Lollis, L.; Parr, C.; McDougald, L. R. (2011). "The Efficacy of Anticoccidial Products against Eimeria spp. in Northern Bobwhites". Avian Diseases. 55 (1): 59–64. doi:10.1637/9572-101310-Reg.1. PMID 21500637. S2CID 30943649.