Bazedoxifene/conjugated estrogens

Bazedoxifene/conjugated estrogens
Combination of
BazedoxifeneSelective estrogen receptor modulator
Conjugated estrogensEstrogen
Clinical data
Trade namesDuavee, Duavive
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa614004
License data
Pregnancy
category
  • AU: D
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
CAS Number
ChemSpider
  • None
KEGG

Bazedoxifene/conjugated estrogens, sold under the brand name Duavee among others, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis. It contains the selective estrogen receptor modulator bazedoxifene and conjugated estrogens. It is taken by mouth.

The combination was approved for medical use in the United States in October 2013, and in the European Union in December 2014.

See also

References

  1. ↑ "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". Drugs.com. 16 February 2019. Retrieved 23 June 2020.
  2. ↑ "Duavive Product information". Health Canada. 9 June 2023. Retrieved 17 February 2025.
  3. 1 2 3 4 "Duavee- conjugated estrogens/bazedoxifene tablet, film coated". DailyMed. 16 July 2021. Retrieved 21 February 2022.
  4. 1 2 "Duavive EPAR". European Medicines Agency (EMA). Retrieved 10 June 2020.
  5. ↑ Palacios S, Mejía Ríos A (February 2015). "Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women". Drugs of Today. 51 (2): 107–16. doi:10.1358/dot.2015.51.2.2281023. PMID 25756066.
  6. ↑ Lello S, Capozzi A, Scambia G (2017). "The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause". International Journal of Endocrinology. 2017 5064725. doi:10.1155/2017/5064725. PMC 5735652. PMID 29358948.
  7. ↑ "Drug Approval Package: Duavee (conjugated estrogens and bazedoxifene) NDA #022247". U.S. Food and Drug Administration (FDA). 7 October 2013. Retrieved 23 June 2020.