EFCAB6

EFCAB6
Identifiers
Aliases	EFCAB6, DJBP, HSCBCIP1, dJ185D5.1, EF-hand calcium binding domain 6
External IDs	MGI: 1924877; GeneCards: EFCAB6
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1WLZ, 5D67
Gene location (Human)
Chr.	Chromosome 22 (human)
End	43,812,337 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	83,949,580 bp
RNA expression pattern
	Top expressed in
	left testis; ; right testis; ; sperm; ; buccal mucosa cell; ; right uterine tube; ; bronchial epithelial cell; ; oocyte; ; testicle; ; olfactory zone of nasal mucosa; ; gonad;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; zygote; ; primary oocyte; ; secondary oocyte; ; muscle of thigh; ; temporal muscle; ; cornea; ; skeletal muscle tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; calcium ion binding;
Cellular component	nucleus; nucleoplasm;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	64800
	77627
	ENSG00000186976
	ENSMUSG00000022441
	Q5THR3
	Q6P1E8
	NM_022785; NM_198856
	NM_001161628; NM_001161629; NM_029946
	NP_073622; NP_942153
	NP_001155100; NP_001155101; NP_084222
	Wikidata
View/Edit Human	View/Edit Mouse

EF-hand calcium-binding domain-containing protein 6 is a protein that in humans is encoded by the EFCAB6 gene.

Interactions

EFCAB6 has been shown to interact with PARK7 and Androgen receptor.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000186976 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022441 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O (Mar 2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.
1 2 3 Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (Mar 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex". Mol Cancer Res. 1 (4): 247–61. PMID 12612053.
↑ "Entrez Gene: FLJ23588 CAP-binding protein complex interacting protein 1".

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. Bibcode:1999Natur.402..489D. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22". Genome Res. 13 (1): 27–36. doi:10.1101/gr.695703. PMC 430954. PMID 12529303.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 22 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000186976 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022441 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11258795-5] Hirosawa M, Nagase T, Murahashi Y, Kikuno R, Ohara O (Mar 2001). "Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping". DNA Res. 8 (1): 1–9. doi:10.1093/dnares/8.1.1. PMID 11258795.

[pmid12612053-6] 1 2 3 Niki T, Takahashi-Niki K, Taira T, Iguchi-Ariga SM, Ariga H (Mar 2003). "DJBP: a novel DJ-1-binding protein, negatively regulates the androgen receptor by recruiting histone deacetylase complex, and DJ-1 antagonizes this inhibition by abrogation of this complex". Mol Cancer Res. 1 (4): 247–61. PMID 12612053.

[entrez-7] "Entrez Gene: FLJ23588 CAP-binding protein complex interacting protein 1".

EFCAB6

Interactions

References

Further reading