FAM3D

FAM3D
Identifiers
Aliases	FAM3D, EF7, OIT1, family with sequence similarity 3 member D, FAM3 metabolism regulating signaling molecule D
External IDs	OMIM: 608619; MGI: 1201784; GeneCards: FAM3D
Gene location (Human)
Chr.	Chromosome 3 (human)
End	58,666,834 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	14,120,836 bp
RNA expression pattern
	Top expressed in
	mucosa of transverse colon; ; rectum; ; mucosa of sigmoid colon; ; nasal epithelium; ; mucosa of ileum; ; olfactory zone of nasal mucosa; ; parotid gland; ; trachea; ; mucosa of pharynx; ; minor salivary glands;
	Top expressed in
	left colon; ; gastric mucosa; ; epithelium of stomach; ; mucous cell of stomach; ; parotid gland; ; duodenum; ; submandibular gland; ; crypt of lieberkuhn of small intestine; ; pyloric antrum; ; Ileal epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	cytokine activity;
Cellular component	extracellular region; membrane; integral component of membrane;
Biological process	negative regulation of insulin secretion; regulation of signaling receptor activity; negative regulation of glucagon secretion; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	131177
	18300
	ENSG00000198643
	ENSMUSG00000021749
	Q96BQ1
	P97805
	NM_138805
	NM_146050
	NP_620160
	NP_666162
	Wikidata
View/Edit Human	View/Edit Mouse

Family with sequence similarity 3, member D is a protein that in humans is encoded by the FAM3D gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000198643 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000021749 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Family with sequence similarity 3, member D". Retrieved 2014-03-09.

Zhu Y, Xu G, Patel A, McLaughlin MM, Silverman C, Knecht K, et al. (August 2002). "Cloning, expression, and initial characterization of a novel cytokine-like gene family". Genomics. 80 (2): 144–150. doi:10.1006/geno.2002.6816. PMID 12160727.
Ramachandran P, Boontheung P, Xie Y, Sondej M, Wong DT, Loo JA (June 2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". Journal of Proteome Research. 5 (6): 1493–1503. doi:10.1021/pr050492k. PMID 16740002.
De Wit NJ, Ijssennagger N, Oosterink E, Keshtkar S, Hooiveld GJ, Mensink RP, et al. (November 2012). "Oit1/Fam3D, a gut-secreted protein displaying nutritional status-dependent regulation". The Journal of Nutritional Biochemistry. 23 (11): 1425–1433. doi:10.1016/j.jnutbio.2011.09.003. PMID 22226334.
Xu B, Roos JL, Dexheimer P, Boone B, Plummer B, Levy S, et al. (August 2011). "Exome sequencing supports a de novo mutational paradigm for schizophrenia". Nature Genetics. 43 (9): 864–868. doi:10.1038/ng.902. PMC 3196550. PMID 21822266.

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