FCMR

FCMR
Identifiers
AliasesFCMR, TOSO, FAIM3, Fc fragment of IgM receptor, Fc mu receptor, FcmuR
External IDsOMIM: 606015; MGI: 1916419; GeneCards: FCMR
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez

9214

69169

Ensembl

ENSG00000162894

ENSMUSG00000042474

UniProt

O60667

A1KXC4

RefSeq (mRNA)

NM_001142472
NM_001142473
NM_001193338
NM_005449

NM_026976

RefSeq (protein)

NP_001135945
NP_001180267
NP_005440

NP_081252
NP_001392822

Location (UCSC)Chr 1: 206.9 – 206.92 MbChr 1: 130.79 – 130.81 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Fc fragment of IgM receptor is a protein that in humans is encoded by the FCMR gene.

Function

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM (see MIM 147020) (Kubagawa et al., 2009 [PubMed 19858324]; Shima et al., 2010 [PubMed 20042454]).

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000162894 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042474 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ "Entrez Gene: Fc fragment of IgM receptor". Retrieved 2016-03-24.

Further reading

  • Sigruener A, Buechler C, Bared SM, Grandl M, Aslanidis C, Ugocsai P, Gehrmann M, Schmitz G (2007). "E-LDL upregulates TOSO expression and enhances the survival of human macrophages". Biochem. Biophys. Res. Commun. 359 (3): 723–8. doi:10.1016/j.bbrc.2007.05.169. PMID 17553462.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.