FKBP7

FKBP7
Identifiers
Aliases	FKBP7, FKBP23, PPIase, FK506 binding protein 7, FKBP prolyl isomerase 7
External IDs	OMIM: 607062; MGI: 1336879; GeneCards: FKBP7
Enzyme activity
Gene location (Human)
Chr.	Chromosome 2 (human)
End	178,478,600 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	76,503,460 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; Achilles tendon; ; left ovary; ; right ovary; ; sperm; ; tendon of biceps brachii; ; smooth muscle tissue; ; canal of the cervix; ; tibia; ; Descending thoracic aorta;
	Top expressed in
	calvaria; ; body of femur; ; lower jaw; ; tooth; ; molar; ; efferent ductule; ; dermis; ; Meckel's cartilage; ; fossa; ; atrioventricular valve;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; FK506 binding; protein binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; metal ion binding;
Cellular component	endoplasmic reticulum lumen; endoplasmic reticulum; cytoplasm;
Biological process	chaperone-mediated protein folding; protein peptidyl-prolyl isomerization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	51661
	14231
	ENSG00000079150
	ENSMUSG00000002732
	Q9Y680
	O54998
	NM_001135212; NM_016105; NM_181342
	NM_010222; NM_001355079; NM_001355080
	NP_001128684; NP_851939
	NP_034352; NP_001342008; NP_001342009
	Wikidata
View/Edit Human	View/Edit Mouse

FK506 binding protein 7 is a protein that in humans is encoded by the FKBP7 gene. The gene is also known as FKBP23 and PPIase. FKBP7 belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. The orthologous protein in mouse is located in the endoplasmic reticulum and binds calcium.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000079150 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002732 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 3 "FK506 binding protein 7". Retrieved 2011-12-06.
↑ Nakamura T, Yabe D, Kanazawa N, Tashiro K, Sasayama S, Honjo T (November 1998). "Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability". Genomics. 54 (1): 89–98. doi:10.1006/geno.1998.5571. PMID 9806833.

Patterson CE, Gao J, Rooney AP, Davis EC (June 2002). "Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family". Genomics. 79 (6): 881–889. doi:10.1006/geno.2002.6777. PMID 12036304.
Matsuda M, Koide T, Yorihuzi T, Hosokawa N, Nagata K (January 2001). "Molecular cloning of a novel ubiquitin-like protein, UBIN, that binds to ER targeting signal sequences". Biochemical and Biophysical Research Communications. 280 (2): 535–540. Bibcode:2001BBRC..280..535M. doi:10.1006/bbrc.2000.4149. PMID 11162551.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000079150 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000002732 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 3 "FK506 binding protein 7". Retrieved 2011-12-06.

[6] Nakamura T, Yabe D, Kanazawa N, Tashiro K, Sasayama S, Honjo T (November 1998). "Molecular cloning, characterization, and chromosomal localization of FKBP23, a novel FK506-binding protein with Ca2+-binding ability". Genomics. 54 (1): 89–98. doi:10.1006/geno.1998.5571. PMID 9806833.

FKBP7

References

Further reading