FNDC3A

FNDC3A

Identifiers

FNDC3A, FNDC3, HUGO, bA203I16.1, bA203I16.5, fibronectin type III domain containing 3A

External IDs

OMIM: 615794; MGI: 1196463; GeneCards: FNDC3A

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
1WK0, 1X3D, 1X4X, 1X5X, 2CRM, 2CRZ

Gene location (Human)

Chr.	Chromosome 13 (human)

Band	13q14.2	Start	48,975,912 bp
Band	13q14.2	End	49,209,779 bp

Gene location (Mouse)

Chr.	Chromosome 14 (mouse)

Band	14 D2\|14 37.62 cM	Start	72,775,386 bp
Band	14 D2\|14 37.62 cM	End	72,947,443 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

corpus epididymis

caput epididymis

jejunal mucosa

cardia

tail of epididymis

germinal epithelium

decidua

islet of Langerhans

mucosa of paranasal sinus

body of pancreas

Top expressed in

parotid gland

decidua

seminal vesicula

median eminence

lacrimal gland

submandibular gland

arcuate nucleus

gastrula

islet of Langerhans

pineal gland

More reference expression data

n/a

Gene ontology
Molecular function	RNA binding
Cellular component	integral component of membrane cytosol Golgi membrane Golgi apparatus acrosomal vesicle membrane cytoplasmic vesicle vesicle membrane
Biological process	fertilization Sertoli cell development spermatid development cell-cell adhesion
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


22862


319448


ENSG00000102531


ENSMUSG00000033487


Q9Y2H6


Q8BX90

RefSeq (mRNA)


NM_001079673 NM_001278438 NM_014923


NM_207636

RefSeq (protein)


NP_001073141 NP_001265367 NP_055738


NP_997519

Location (UCSC)

Chr 13: 48.98 – 49.21 Mb

Chr 14: 72.78 – 72.95 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Fibronectin type-III domain-containing protein 3a is a protein that in humans is encoded by the FNDC3A gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000102531 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000033487 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: FNDC3A fibronectin type III domain containing 3A".

Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Carrouel F, Couble ML, Vanbelle C, et al. (2008). "HUGO (FNDC3A): a new gene overexpressed in human odontoblasts". J. Dent. Res. 87 (2): 131–6. doi:10.1177/154405910808700209. PMID 18218838. S2CID 27513925.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. Bibcode:2004Natur.428..522D. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

PDB gallery

1wk0: Solution structure of Fibronectin type III domain derived from human KIAA0970 protein
1x3d: Solution structure of the fibronectin type-III domain of human fibronectin type-III domain containing protein 3a
1x4x: Solution structure of the 6th fibronectin type III domain from human fibronectin type III domain containing protein 3
1x5x: Solution structure of the fibronectin type-III domain of human fibronectin type III domain containing protein 3
2crm: Solution structure of the fourth FNIII domain of human
2crz: Solution structure of the fifth FNIII domain of human fibronectin type III domain containing protein 3a

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