Flufenauxirim

Flufenauxirim

Names
Preferred IUPAC name 6-amino-2-[2-fluoro-3-methoxy-4-(trifluoromethyl)phenyl]-5-methoxypyrimidine-4-carboxylic acid
Other names Flufenauxirime
Identifiers
CAS Number	3054208-46-4
3D model (JSmol)	Interactive image
PubChem CID	172914557
UNII	J83HET9TZJ Y
InChI InChI=1S/C14H11F4N3O4/c1-24-9-6(14(16,17)18)4-3-5(7(9)15)12-20-8(13(22)23)10(25-2)11(19)21-12/h3-4H,1-2H3,(H,22,23)(H2,19,20,21) Key: WNQNYSQIBVZMHA-UHFFFAOYSA-N
SMILES COC1=C(C=CC(=C1F)C2=NC(=C(C(=N2)N)OC)C(=O)O)C(F)(F)F
Properties
Chemical formula	C14H11F4N3O4
Molar mass	361.253 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Flufenauxirim is a chemical herbicide. It is a pyrimidinecarboxylic acid and a broad-spectrum herbicide. Its mechanism of action is unclear, but likely involves inhibition of enzymes that are involved in synthesis of fatty acids and amino acids. The formula of flufenauxirim is C₁₄H₁₁F₄N₃O₄.

The herbicide was announced in March 2025 as a product of Chinese company Qingdao KingAgroot Chemical Compound Co., and was provisionally approved by the International Organization for Standardization. It is noted as being effective against grasses and broadleaf weeds. As of August 2025, it is not approved by any European regulatory authority.

Production and synthesis

Flufenauxirim is produced through a substitution reaction between pyrimidine and an aromatic intermediate that is substituted with methoxy and fluorine groups. A derivative of flufenauxirim is flufenauxirim-metotyl.

References