GALNT11

GALNT11
Identifiers
Aliases	GALNT11, GALNACT11, GALNAC-T11, polypeptide N-acetylgalactosaminyltransferase 11
External IDs	OMIM: 615130; MGI: 2444392; GeneCards: GALNT11
Enzyme activity
Gene location (Human)
Chr.	Chromosome 7 (human)
End	152,122,347 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	25,470,916 bp
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; renal medulla; ; kidney tubule; ; retinal pigment epithelium; ; Brodmann area 23; ; glomerulus; ; middle temporal gyrus; ; metanephric glomerulus; ; lateral nuclear group of thalamus; ; tibia;
	Top expressed in
	right kidney; ; proximal tubule; ; human kidney; ; vestibular membrane of cochlear duct; ; vestibular sensory epithelium; ; decidua; ; visual cortex; ; primary visual cortex; ; yolk sac; ; condyle;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; glycosyltransferase activity; metal ion binding; Notch binding; carbohydrate binding; polypeptide N-acetylgalactosaminyltransferase activity;
Cellular component	integral component of membrane; Golgi apparatus; membrane; Golgi membrane;
Biological process	Notch signaling pathway; cilium assembly; protein glycosylation; protein O-linked glycosylation via threonine; determination of left/right symmetry; O-glycan processing; Notch receptor processing; regulation of Notch signaling pathway; Notch signaling involved in heart development;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	63917
	231050
	ENSG00000178234
	ENSMUSG00000038072
	Q8NCW6
	Q921L8
	NM_001304514; NM_022087
	NM_144908; NM_001359890
NP_001291443; NP_071370; NP_001358387; NP_001358388; NP_001358389;
	NP_001358390; NP_001358391; NP_001358392; NP_001358393; NP_001358394; NP_001358395; NP_001358396; NP_001358397; NP_001358398; NP_001358399; NP_001358400; NP_001358401; NP_001358402; NP_001358403; NP_001358404
	NP_659157; NP_001346819
	Wikidata
View/Edit Human	View/Edit Mouse

Polypeptide N-acetylgalactosaminyltransferase 11 is an enzyme that in humans is encoded by the GALNT11 gene.

The GALNT11 gene contains 10 exons. An important paralog of this gene is GALNTL5.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000178234 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038072 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, et al. (June 2002). "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila". The Journal of Biological Chemistry. 277 (25): 22623–22638. doi:10.1074/jbc.M202684200. PMID 11925450.
↑ "GALNT11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)". Entrez Gene.
↑ "UDP-N-Acetyl-Alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 11; GALNT11". OMIM.
↑ "GALNT11 Gene (Protein Coding)". GeneCards.

Sanger Centre T, Washington University Genome Sequencing Cente T (November 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi:10.1101/gr.8.11.1097. PMID 9847074.
Brandenberger R, Wei H, Zhang S, Lei S, Murage J, Fisk GJ, et al. (June 2004). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nature Biotechnology. 22 (6): 707–716. doi:10.1038/nbt971. PMID 15146197. S2CID 27764390.
Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, et al. (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000178234 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000038072 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[Schwientek_2002-5] Schwientek T, Bennett EP, Flores C, Thacker J, Hollmann M, Reis CA, et al. (June 2002). "Functional conservation of subfamilies of putative UDP-N-acetylgalactosamine:polypeptide N-acetylgalactosaminyltransferases in Drosophila, Caenorhabditis elegans, and mammals. One subfamily composed of l(2)35Aa is essential in Drosophila". The Journal of Biological Chemistry. 277 (25): 22623–22638. doi:10.1074/jbc.M202684200. PMID 11925450.

[entrez-6] "GALNT11 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)". Entrez Gene.

[7] "UDP-N-Acetyl-Alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 11; GALNT11". OMIM.

[8] "GALNT11 Gene (Protein Coding)". GeneCards.

GALNT11

References

Further reading