GET4

GET4

Identifiers

GET4, C7orf20, CEE, TRC35, CGI-20, golgi to ER traffic protein 4, guided entry of tail-anchored proteins factor 4

External IDs

OMIM: 612056; MGI: 1914854; GeneCards: GET4

Gene location (Human)

Chr.	Chromosome 7 (human)

Band	7p22.3	Start	876,554 bp
Band	7p22.3	End	896,436 bp

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)

Band	5\|5 G2	Start	139,238,079 bp
Band	5\|5 G2	End	139,255,806 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

left testis

right testis

pituitary gland

right adrenal cortex

left adrenal cortex

right uterine tube

anterior pituitary

right lobe of liver

skin of leg

skin of abdomen

Top expressed in

bone marrow

yolk sac

epiblast

layer of retina

neural layer of retina

proximal tubule

neural tube

adrenal gland

limb

lip

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding chaperone binding
Cellular component	BAT3 complex cytosol cytoplasm nucleoplasm nucleolus
Biological process	cytoplasmic sequestering of protein tail-anchored membrane protein insertion into ER membrane maintenance of unfolded protein involved in ERAD pathway protein insertion into ER membrane
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51608


67604


ENSG00000239857


ENSMUSG00000025858


Q7L5D6


Q9D1H7

RefSeq (mRNA)


NM_015949


NM_001163316 NM_026269 NM_001359238

RefSeq (protein)


NP_057033


NP_001156788 NP_080545 NP_001346167

Location (UCSC)

Chr 7: 0.88 – 0.9 Mb

Chr 5: 139.24 – 139.26 Mb

PubMed search

View/Edit Human

View/Edit Mouse

GET4 is a protein that in humans is encoded by the GET4 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000239857 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000025858 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: C7orf20 chromosome 7 open reading frame 20".

External links

Human GET4 genome location and GET4 gene details page in the UCSC Genome Browser.

Further reading

Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology". Science. 300 (5620): 767–72. Bibcode:2003Sci...300..767S. doi:10.1126/science.1083423. PMC 2882961. PMID 12690205.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

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