Gregoire River is a tributary of the Athabasca River in Alberta, Canada. It is the only outflow of Willow Lake.
The river is a migration route for the northern pike, longnose sucker, and white sucker.
Gregoire River has the name of a pioneer citizen.
56°29′01″N 110°48′06″W / 56.48352°N 110.80178°W