H1FX

H1-10
Identifiers
Aliases	H1-10, H1X, H1.10, H1 histone family member X, H1FX, H1.10 linker histone
External IDs	OMIM: 602785; MGI: 2685307; GeneCards: H1-10
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LSO
Gene location (Human)
Chr.	Chromosome 3 (human)
End	129,316,286 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	87,958,619 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; olfactory zone of nasal mucosa; ; thymus; ; ectocervix; ; right ovary; ; skin of abdomen; ; right uterine tube; ; left ovary; ; left uterine tube;
	Top expressed in
	ventricular zone; ; adrenal medulla; ; ganglionic eminence; ; white adipose tissue; ; striatum of neuraxis; ; lens; ; testicle; ; neural tube; ; primary visual cortex; ; superior frontal gyrus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA binding; cadherin binding; double-stranded DNA binding; protein binding; nucleosomal DNA binding;
Cellular component	nucleosome; nucleolus; nucleus; chromosome;
Biological process	nucleosome assembly; regulation of transcription, DNA-templated; chromosome condensation; negative regulation of DNA recombination;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	8971
	243529
	ENSG00000184897
	ENSMUSG00000044927
	Q92522
	Q80ZM5
	NM_006026
	NM_198622
	NP_006017
	NP_941024
	Wikidata
View/Edit Human	View/Edit Mouse

Histone H1x is a protein that in humans is encoded by the H1FX gene.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H1 family.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000184897 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000044927 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Yamamoto T, Horikoshi M (Dec 1996). "Cloning of the cDNA encoding a novel subtype of histone H1". Gene. 173 (2): 281–285. doi:10.1016/0378-1119(96)00020-0. PMID 8964515.
↑ Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656. S2CID 38539096.
1 2 "Entrez Gene: H1FX H1 histone family, member X".

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Histone H1x

This article on a gene on human chromosome 3 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000184897 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000044927 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8964515-5] Yamamoto T, Horikoshi M (Dec 1996). "Cloning of the cDNA encoding a novel subtype of histone H1". Gene. 173 (2): 281–285. doi:10.1016/0378-1119(96)00020-0. PMID 8964515.

[pmid9439656-6] Albig W, Doenecke D (Feb 1998). "The human histone gene cluster at the D6S105 locus". Hum Genet. 101 (3): 284–294. doi:10.1007/s004390050630. PMID 9439656. S2CID 38539096.

[entrez-7] 1 2 "Entrez Gene: H1FX H1 histone family, member X".

H1FX

References

Further reading

External links