Hamilton Morris | |
|---|---|
Morris in 2019 | |
| Born | April 14, 1987 |
| Other name | D. H. Ticklish |
| Education | The University of Chicago; The New School (BSc) |
| Occupations | Journalist; Filmmaker; Chemist; Scientist |
| Years active | 2008–present |
| Employer(s) | Vice Media; University of the Sciences's Philadelphia College of Pharmacy; Compass Pathways |
| Known for | Psychoactive drug journalism and research |
| Notable work | Hamilton's Pharmacopeia (TV show) (alt); Hamilton's Pharmacopeia (web series); The Hamilton Morris Podcast |
| Parents |
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| Website | hamiltonmorris patreon |
Hamilton Morris (born April 14, 1987) is an American journalist, filmmaker, chemist, and scientific researcher. He is most well-known for his television series Hamilton's Pharmacopeia, which aired from 2016 to 2021 and covered the chemistry, history, and cultural impact of various psychoactive drugs, particularly psychedelics. Morris also started a podcast called The Hamilton Morris Podcast in 2020. He is considered to be among the leading psychoactive drug journalists.
Morris was born in New York City, the son of Julia Sheehan, an art historian, and documentary filmmaker Errol Morris. He is Jewish. Morris was raised in Cambridge, Massachusetts. He has described being a pyromaniac and interested in explosives and poisons as a child. In his teenage years, he appeared in television commercials, notably a 2002 advertisement for the first-generation iPod.
Morris first explored psychoactive drugs by trying Salvia divinorum with a friend in high school as a teenager, which left him in a state of "astonishment" and led him to learn how to chemically extract salvinorin A from the plant. However, it was not until Morris learned about Alexander Shulgin and novel research chemicals via a New York Times article a few years later in 2005 that he became more interested in and "obsessed" with psychoactive drugs. Relatedly, Morris discovered and began frequenting psychoactive drug websites such as Bluelight and Erowid.
Morris attended the University of Chicago and The New School, where he studied anthropology and chemistry, including under the psychedelic drug expert Nicolas Langlitz. He earned a bachelor of science (BSc) degree in liberal arts from The New School, with his credential described as a "weird interdisciplinary science degree".
Morris began writing for Vice magazine as a college sophomore in February 2008. He initially published under the pseudonym "D. H. Ticklish", with his first article being an Alexander Shulgin-esque write-up of his experiences with ten mostly obscure psychedelic drugs. Subsequently, Morris began writing under his real name and published a piece called "The Magic Jews" in 2008 documenting his experience taking LSD with a group of Hasidic Jews. Vice later hired him to write a monthly print column titled "Hamilton's Pharmacopeia" in 2009 that evolved into a series of articles and documentaries for VBS.tv focused on psychoactive drugs. He was the science editor of Vice magazine in Manhattan by 2013. Morris has also written for Harper's Magazine and the The Brooklyn Rail.
In his Hamilton's Pharmacopeia web series for Vice Media, which ran from 2009 to 2016 and spanned 11 episodes, Morris covered topics including Phyllomedusa bicolor (sapo or kambo), Haitian zombies and tetradotoxin, Alexander and Ann Shulgin, Krystle Cole and William Leonard Pickard, magic truffles, sensory deprivation tanks with Joe Rogan, zolpidem, efavirenz, cannabinoids, and Matt Bowden. Morris subsequently did his Viceland show Hamilton's Pharmacopeia, which ran for three seasons and spanned 20 episodes, from 2016 until 2021. The show had episodes covering a variety of psychoactive drugs, including LSD, psilocybin, mescaline, bufotenin, DMT, 5-MeO-DMT, methamphetamine, methaqualone (Quaaludes), phencyclidine (PCP), ketamine, xenon, ibogaine, kratom, Salvia divinorum, Amanita muscaria, and hallucinogenic fish, among others. In one episode, Morris revealed Ken Nelson as the author of the 1984 Bufo Alvarius: the Psychedelic Toad of the Sonoran Desert pamphlet, which described how to use Incilius alvarius toad venom containing 5-MeO-DMT as a psychedelic drug. Other topics that Morris has covered or been interested in covering include the Temple of the True Inner Light, Lizard Labs, Ariadne, and 7-OH.
Morris worked part-time as a chemist and pharmacologist in Jason Wallach's lab at the University of the Sciences's Philadelphia College of Pharmacy for more than a decade, from 2010 until at least late 2022. He has coauthored scientific papers on hallucinogens with Wallach, including a 2014 review on dissociatives and a 2023 study identifying serotonergic psychedelics as mediating hallucinogenic-like effects (i.e., the head-twitch response) via activation of the serotonin 5-HT2A receptor Gq signaling pathway. In September 2021, Morris left Vice to work as a full-time chemistry consultant at the biotechnology startup, Compass Pathways. Wallach's lab has a contract with Compass Pathways to develop novel psychedelic therapeutics. Although Morris left Vice, he said that he plans to continue to write, podcast, and make additional films in the future. In 2020, Morris started an ongoing podcast called The Hamilton Morris Podcast, interviewing people from the psychoactive drug world.
Morris has personally developed and tested novel psychoactive drugs, such as the psychedelic lysergamide FP-LAD and the tellurium-containing psychedelic phenethylamine 2C-Te. In addition, he has explored and helped characterize obscure existing psychoactive drugs. As an example, Morris reported in the early 2020s, based on self-experimentation and following earlier work by Jonathan Ott, that bufotenin is indeed active as a psychedelic. According to Morris, the effects of this drug are like a cross between those of DMT and 5-MeO-DMT. Other novel psychoactive drug examples characterized by Morris include efavirenz, gaboxadol, and α,N,N-trimethyltryptamine (α,N,N-TMT). Yet another example is pharmahuasca in the form of the combination of DMT and the synthetic monoamine oxidase inhibitor (MAOI) moclobemide. Besides the preceding informal examples, Morris and Wallach have extensively studied the auditory psychedelic diisopropyltryptamine (DiPT).
Morris has an ongoing conflict with the psychedelic media organization and self-described "watchdog group" Psymposia.
Morris is considered to be among the world's leading psychoactive drug journalists. His work has been described as gonzo journalism analogous to that of Hunter S. Thompson. In addition, Morris has been said to be "doing for drugs what Anthony Bourdain did for food". He has been credited with helping to change the way society thinks and talks about drugs, with efforts towards the end of drug prohibition.
Morris describes himself as scientifically oriented, a hardened and cynical atheist and materialist, and "not spiritual at all", though he is sympathetic to spiritual and shamanic traditions employing entheogens. Some of his personal heroes and influences include Wade Davis and Alexander Shulgin. Morris is a psychonaut and has extensively experimented with psychoactive drugs. He believes in the right to personal freedom regarding psychoactive drugs and altered states of consciousness, has prominently criticized the war on drugs as unsuccessful, harmful, and counterproductive, and advocates for the legalization of all drugs. Morris has been diagnosed with attention deficit hyperactivity disorder (ADHD) and takes stimulant medication for his symptoms. He has also used nootropics.
Some notable projects of Morris include:
[...] His first article for Vice was a roundup of emerging psychoactive drugs, which he wrote under a pseudonym, D.H. Ticklish, while he was studying at the New School and for which he was paid nothing. "I was a sophomore in college, so it seemed like a lot," he said. [...]
I have spent the last year of my life on an exhausting psychedelic journey. I managed to get my hands on some of the most potent and rare hallucinogenic drugs ever made, drugs that mainly are illegal. [...]
Morris's first meaningful drugs experience came at age 13, "in my friend's Volvo, smoking salvia and crying tears of joy". He felt, he recalls, "just astonishment that those states are even possible, that anyone can reach them so effortlessly."
Morris's interest in chemistry started as a child, when he, like many young scientists, developed a curiosity about explosives and poisons. As a teenager, Morris's fascination with chemistry and psychoactive drugs converged when he extracted salvinorin A from salvia leaves.
The Hamilton Morris Podcast: Best known as the creator and host of the VICE docuseries "Hamilton's Pharmacopeia," journalist Hamilton Morris has found quite a following in his quest to understand and explain the history, chemistry, and promise of psychoactive drugs. He primarily shares content on Patreon, releasing three or four new episodes each month for subscribers, but makes some episodes free on other platforms. (That means you'll have to subscribe if you want to hear the most recent episodes.) [...]
I had my first psychedelic experience smoking salvia in a friend's station wagon when I was 16. [...] To take a moment and clarify my religious background: I am a Jew. [...] In short, I know nothing about Judaism. I am also not religious or "spiritual" in any way.
I first became interested in salvia as a teenager when I extracted and purified salvinorin A, leading to a lifelong interest in psychedelics and chemistry.
Morris himself fell headfirst into the rabbit hole of research chemical culture when he read about Shulgin in The New York Times Magazine's 2005 article. Though Morris was scientifically interested in drugs throughout high school, his chemical experimentation never went beyond salvia and the extraction of salvinorin A. Teenage drug culture didn't appeal to him, and he found his school's druggie population off-putting. His horizons expanded greatly after his college-age exposure to Shulgin and once he started to monitor the on-line research chemical market. "That's when I really became obsessed," he said.
[...] I remember, as a high school student, reading a profile of [Alexander Shulgin] in the New York Times Magazine, sitting in my parents' kitchen, and thinking, and I wasn't even very interested in drugs, I was probably a little bit more interested than a typical high school student, but I wasn't a druggie. I had smoked salvia and cannabis a number of times and drank alcohol a number of times, but I wasn't actively pursuing this. And then, I read a profile of this guy and thought wow, he is inventing not only new drugs but new types of drugs. [...] And I became pretty seriously obsessed with him. Ordered his books, read the books. [...]
[...] what might be surprising to C&EN's readers is his knowledge of chemistry. He clearly knows his indoles from his indazoles. In the HBO piece, the word "rotovap" rolls off his tongue like he's stripped some solvent himself. Morris tells C&EN that, in addition to taking undergraduate courses in general and organic chemistry, he's spent time doing organic synthesis and has even published in scholarly journals, [...]
The son of famed documentary filmmaker Errol Morris (The Thin Blue Line, The B-Side and The Fog of War), Hamilton Morris first started writing for Vice under a pseudonym. According to a 2015 profile in The New York Times, "his first article for Vice was a roundup of emerging psychoactive drugs, which he wrote under a pseudonym, D.H. Ticklish."
[Morris:] I got very close to a psychedelic cult for a while [...] I was writing a story about [...] it went sour with them. [...] maybe I'll write something about them at some point for an article in Harper's. This was like one of the things that was contributing to my depression in 2018. [...] I was not—although I did actually try to join this cult as a freshman in college—uh, I was never a member of this cult. I was involved with them via a strange series of connections and was ultimately trying to write a story about them [...]
The Temple of the True Inner Light is a New York City-based religion that worships the psychedelic tryptamine DPT as their sacrament. They have existed in some form since the 1970s and in a extremely reduced capacity exist to this day. And it's been brought up a few times that I was working on a big project about the Temple of the True Inner Light. I actually spent the majority of the year 2018 intensively involved in researching them. [...] I navigated [these difficulties] in part by not publishing the article. [...] I will publish something one day. I do have the article basically written. I just need to navigate some of these remaining issues.
I find you know, bufotenine, to me feels almost emblematic of a, of the kind of tired, tired mind tryptamine experience where you can't really speak. You can't really, you know, pure bufotenine base is about equal potent with DMT. You know, 50 milligrams or so produces a very powerful experience, but it has, it's kind of an awkward middle child between DMT and 5-MeO-DMT, chemically, pharmacologically and experientially, where it has, it's more dissociative than DMT less dissociative than 5-MeO-DMT, more visual than 5-MeO-DMT, but less visual than DMT. And far more nauseatingly than either of them. And, and so it's kind of there's a reason, I think that it has never quite caught on despite the fact that it is indisputably a classical psychedelic. And I, one of those things is that kind of softness of the thoughts on it, you're kind of in a soupy mindset, where it becomes I think, a little bit harder to articulate and integrate any of the ideas that come to you.Transcript.
[Morris:] I've used [bufotenine] a couple times, once at 50 milligrams of the freebase snorted. [...] I found it to be extremely nauseating. I found it to be qualitatively intermediate between 5-MeO-DMT and DMT in that it was more visual than my experiences with 5-MeO-DMT but less visual than my typical experiences with DMT. It had a longer duration than 5-MeO-DMT and maybe even a longer duration than DMT as well. It was about an hour. Although I don't have all that much experience snorting DMT freebase.
[Morris:] Bufotenine is a drug that I have tried. I've tried isolated pure bufotenine and it is a psychedelic that is both pharmacologically and experientially and chemically intermediate between DMT and 5-MeO-DMT. So it has a longer duration than actually both 5-MeO-DMT and DMT. It's yet less visual than DMT but more visual than 5-MeO-DMT, so it's kind of like in-between the two. It's also very nauseating, which is the main reason that people seem not to enjoy it very much. But it is a classical psychedelic drug that produces visionary effects. And Jonathan Ott actually liked the effect of it quite a bit.
Acknowledgements: With special thanks to Jason Wallach, Hamilton Morris, and Jitka Nykodemova for their passion and expertise on the topic.
So for anyone listening to this who's followed my work for a while I'm often asked some variation of a question like what is your favorite drug or what is the most interesting drug in the world to you. And I always say oh I don't know, you know, I can't answer [...] but the answer was DiPT. I didn't ever say DiPT because I was afraid that if I drew any attention to it that I would raise its profile in some way and the result would be DiPT being prohibited. And the reason that I cared about DiPT so much was not because it's my favorite drug in the sense that I enjoy it recreationally. The reason is that I've spent about 13 years studying DiPT with Jason and none of this research has been published. This has been an extremely labor-intensive ongoing labor of love that we have done with no external funding for countless hours [...]
Mr. Morris will testify that he is a journalist, documentarian, and medicinal chemist working at Saint Joseph's University in Philadelphia. Mr. Morris has been studying the history, chemistry and pharmacology of DiPT with Dr. Wallach for 13 years. During this time they have synthesized and pharmacologically evaluated a number of DiPT structural analogs with the hope of identifying DiPT's mechanism of action. He qualifies as an expert in the field of chemistry, and will further testify as a fact witness to provide a summary of the medical and scientific literature presently known on the subject of DiPT. [...]
We write reluctantly and by force of circumstance, since the suggestion which one of us made that we are witnessing a dubious "entrepreneurship of psychedelic negativity" was recently taken up by the influential documentary-maker, chemist, and advocate for psychedelic decriminalization, Hamilton Morris (2025). While we respect Morris's wider work in psychedelics and his advocacy around decriminalization, we distance ourselves from his more ad personam attacks against members of Psymposia, as we do from ad personam attacks against Morris. [...]
Hamilton Morris, another prominent figure in the psychedelic field and creator of the popular television series "Hamilton's Pharmacopeia," was one of the conference's speakers. With a distinct air of condescension, Morris attacked critics of the "psychedelic-industrial complex." He mocked Psymposia members Brian Pace and Neşe Devenot's work on right-wing psychedelia and the "moralizing, hand-wringing" critiques of intellectual property in the psychedelic sector, like Shayla Love's award-winning series in VICE.
[...] for someone like me that is an atheist materialist sort of scientifically oriented person [psychedelics] offer what is maybe the closest type of experience to a religious experience.
I am a hardened materialist you know I love science I have a really profound love for science and I think it's the best tool we have for understanding these states and I've never felt that mysticism was necessary to explain things.
Although I am a materialist in the sense that I don't believe in the supernatural, I think that many spiritual traditions and shamanic traditions have a tremendous amount to contribute in terms of the ways that they construct the experience. [...]