Immunomodulation is modulation (regulatory adjustment) of the immune system. It has natural and human-induced forms, and thus the word can refer to the following:
Homeostasis in the immune system, whereby the system self-regulates to adjust immune responses to adaptive rather than maladaptive levels (using regulatory T cells, cell signaling molecules, and so forth)
Immunomodulation as part of immunotherapy, in which immune responses are induced, amplified, attenuated, or prevented according to therapeutic goals.
↑Strzelec, M.; Detka, J.; Mieszczak, P.; Sobocińska, M.K.; Majka, M. (2023). "Immunomodulation-a general review of the current state-of-the-art and new therapeutic strategies for targeting the immune system". Front Immunol. 2023 Mar 9;14:1127704. doi: 10.3389/fimmu.2023.1127704. PMID: 36969193; PMCID: PMC10033545.