The show was originally aired on Saturdays, began from March 20, 1999, to November 17, 2001, replacing Tropang Trumpo and moved to Fridays from November 23, 2001, to March 7, 2003, to compete with GMA 7's Bubble Gang. From March 16, 2003, to February 15, 2004, the show was reformatted with its new title Ispup Atbp. and moved to Sundays, replacing the former timeslot of The Price is Right and was replaced by PBA on ABC.
The program was known for its extensive use of political satire and parodies poking fun at various aspects of Filipino and occasionally foreign pop culture, solely focusing on the popularity and sometimes notoriety of celebrities, television shows, and political figures. When the show was reformatted in 2003, original sketches were added.
Before and after the show's duration, a disclaimer was presented in the style of the Star Wars opening crawl to the music of Carl Orff's Carmina Burana, stating that the parodies were taken from television shows, commercials, and movies with permission, ending up as the show's tagline: "Walang pikunan, ispup onli." which literally translate into "Do not be offended, it's only a spoof."
Alam Morena Clara - a parody of the telenovela Morena Clara
Ang Sangang Daan (lit.'The Branched-Out Path') - a parody of religious program Ang Dating Daan (lit.'The Old Road') and its rival Ang Tamang Daan (lit.'The Right Road'), hosted by John Lapus and Leo Martinez
Balitang Ka!/Balitang Y2K (lit.'You're the News!/Y2K News') - a parody of ABS-CBN public affairs program Balitang K
Bituin La Fea (lit.'The Ugly Star')- a parody of the Colombian telenovela Betty, La Fea (lit.'Betty the Ugly')
Crispy Per Minute - a parody of ABS-CBN showbiz-oriented show Cristy Per Minute (the latter became a radio program, which currently airs over 105.9 True FM).
‘Di Bati sina Mards at Pards (lit.'Sis and Bro are at Loggerheads') - a parody of the GMA public affairs program Debate with Mare at Pare (lit.'Debate with Sis and Bro')
Familiar Feud - parody of the Philippine version of US game show Family Feud which was aired on the same network, ABC in 2001–2002, GMA in 2008–2011 and 2022–present, and ABS-CBN in 2016–2017.
Gay KNB? (lit.'Are You Now Gay?') - a parody of ABS-CBN game show Game KNB? (lit.'Are You Now Game?')
Intrigador (lit.'Intriguer') - a parody of GMA public affairs program Imbestigador (lit.'Investigator')
Kirira: Ano ang Kulay ng Pinipig? (lit.'Kirira: What is the Color of Pinipig?') - a parody of TAPE Inc. and GMA's teledrama Kirara: Ano ang Kulay ng Pag-ibig? (lit.'Kirara: What is the Color of Love?')
Medyo Alas Singko Y Medya (lit.'Nearly Five Thirty') - a parody of ABS-CBN morning show Alas Singko Y Medya. (lit.'Five Thirty')
MKB - a parody of ABS-CBN noontime variety show MTB.
Morning Gays - a parody of ABS-CBN talk show Morning Girls.
Mula Sa Pusa (lit.'From The Cat') - a parody of ABS-CBN teleserye Mula sa Puso (lit.'From The Heart').
Munch - a parody of the GMA talk show Brunch.
No One Can Be A Millionaire? - a parody of the Philippine version of the UK game show Who Wants to Be a Millionaire?, with actors playing celebrities and political figures as contestants, none of whom win the ultimate prize.
Palpakners Jay and Mel (lit.'Failed Partners Mel and Jay') - a parody of GMA Sunday talk show Partners Mel and Jay
Palso: Action Balita (lit.'Fake: Action News') - a parody of ABS-CBN newscast Pulso: Aksyon Balita (lit.'Pulse: Action News')
Pangako Sa Yo Sa Puso Ko Iibigan Kita Hanggang Sa Dulo ng Walang Hanggan (lit.'I Promise To You In My Heart I Will Love You Until The End of Eternity') - a cross-over parody of three ABS-CBN teleseryes.
Pinoy Over Exposed - a parody of ABS-CBN reality show Pinoy Exposed.
The Priest is Right - a parody of the Philippine version of the US game show The Price Is Right which was aired on ABC 5 in 2001–2003, hosted by Willie Nepomuceno as His Eminems Jaime Cardinal Sins and actors playing political figures as contestants.
Pulpol (lit.'Stupid') - a parody of ABS-CBN telemagazine show Pipol (lit.'People')
Rosalinta - a parody of Rosalinda played by Rufa Mae Quinto impersonating Thalía. The name is a parody of Rosalinda and linta (lit.'leech')
Sailor Quarter Moon - a parody of the Japanese superheroine anime Sailor Moon
Sports Ang Limited (lit.'Sports Is Limited') - a parody of ABS-CBN sports program Sports Unlimited.
StarTruck - a parody of GMA talent search program StarStruck
Stirtalk - a parody of GMA showbiz-oriented show Startalk.
Taksil! (lit.'Traitor!') - a parody of GMA newscast Saksi (lit.'Witness')
Wrong Page: Ulat ni Mel Tiongke (lit.'Wrong Page: Report by Mel Tiongke') - a parody of GMA newscast Frontpage: Ulat ni Mel Tiangco (lit.'Frontpage: Report by Mel Tiangco')
Several commercial parodies
Lucky Me!, a popular noodle brand, and Gilbey's Gin also sponsored spoof portions of this program with permission. As a result of growing popularity, Gilbey's Gin and Ispup made a promo for the best Gilbey's spoof in 2002.
Impersonations
Kurita Chances - from ABS-CBN presenter Korina Sanchez, played by Rufa Mae Quinto
Sherap Entrada - from president Joseph Estrada, played by Willie Nepomuceno, and later Jon Santos
Kirira - from Philippine drama Kirara, played by Candy Pangilinan
Senator Koren or Loren Lagarista - from Senator Loren Legarda.
Cong. Manhik-Manaog - a character popularized by Leo Martinez, who used to be a co-star to Mr. Shooli (played by Jun Urbano) in Mongolian Barbecue, was reprised in Ispup through the Barangay Gaya-Gaya segment
Ka Hermie Barong - from weather anchor Ernie Baron, played by Caloy Alde
Edu Manzanas or Dudes - from Edu Manzano, played by Leo Martinez.
Ches Melon- from ABS-CBN News anchor Ces Drilon, played by Candy Pangilinan
Tita Cory Pepino - from president Corazon Aquino, played by Madeleine Nicolas. Tita means "aunt" in Filipino.
Kris Pepino - from Kris Aquino, played by Rufa Mae Quinto, later replaced by Candy Pangilinan after Quinto left the show for Bubble Gang in 2001.
Ramon Revillame or Bong Gabilla - from former action star and senator Ramon Revilla Sr. The surname may be a reference to Willie Revillame
Charing Todos Los Santos Conscious na Conscious (lit.'Kidding All Saints Extremely Conscious') - from TV executive Charo Santos-Concio, played by Jon Santos
David Semplang - from Battle of the Brains presenter and ANC anchor David Celdran, played by Jon Santos. Semplang means "to trip" or "fall down" in Filipino.
His Eminems Jaime Cardinal Sins - from Manila Archbishop Cardinal Jaime Sin.
Mel Tiongke - from GMA News anchor Mel Tiangco, played by Candy Pangilinan
Mayor Vi - from actress and Batangas representative Vilma Santos, played by Jon Santos
Bogie Molcasid - from Ogie Alcasid played by Leo Martinez
Gloring Macabagal-Barroyo - from President Gloria Macapagal Arroyo played by Candy Pangilinan
Nur Miswa - from MNLF chair Nur Misuari played by Willie Nepomuceno
