Jamie Isenstein is an American artist.
Jamie Isenstein works in sculpture, drawing, and performance. In conversation with Friday Arts on the occasion of the 2025 exhibition Body / Body / Body, in which her work was shown alongside Fabienne Lasserre and Sophy Naess, Isenstein stated: "My work has always grappled with political questions, especially work that uses disembodied body parts. When I use my own body, or now other people’s—sometimes it's a hand or feet or a leg—there's this question of subject and object. Am I the subject or have I become an object? There are questions of power. Am I going to be the object and be the thing that power is acted upon, or am I making an object into a subject that has some sort of agency?"
Isenstein has received numerous reviews and mentions in the art press. Her work has been described by art critic Roberta Smith as "cryptic and light, with an undertow of sorrow." The critic David Velasco described her signature as "sculptures that use parts of her own living body as material".