Denison was the senior pastor of Park Cities Baptist Church in Dallas, Texas, from 1998 to 2009. He served as pastor of Second-Ponce de Leon Baptist Church in Atlanta from 1994 to 1998, and from 1988 to 1994, he pastored First Baptist Church Midland.
In February 2009, he cofounded Denison Forum, one of four brands within Denison Ministries. It was formerly known as the Center for Informed Faith, an independent ministry hosted by the Baptist General Convention of Texas.
Denison writes The Daily Article, a weekday email newsletter that comments on current issues through a biblical lens.
He holds a number of fellowships, including:
Denison's perspectives have been published in the Huffington Post, Religion News, the Baptist Standard, Fox News, Patheos, the Dallas Morning News, Baptist News Global, Faithwire, and the Christian Post.
He is the author of multiple books including:
The Coming Tsunami: Why Christians Are Labeled Intolerant, Irrelevant, Oppressive, and Dangerous—and How We Can Turn the Tide
Respectfully, I Disagree: How to Be a Civil Person in an Uncivil Time
How Does God See America?
Biblical Insight to Tough Questions: Vols. 1–10
Bright Hope for Tomorrow: How Jesus' Parables Illuminate Our Darkest Days
Radical Islam: What You Need to Know
The Bible -- You Can Believe It: Biblical Authority in the Twenty-First Century
Myth and the Manger
Life on the Brick Pile:Answers to Suffering from the Letters of Revelation
Seven Crucial Questions About the Bible
Personal life
Denison and his wife, Janet, live in Tyler, Texas. They have two married sons and four grandchildren.