KAT8 regulatory NSL complex subunit 2

KANSL2
Identifiers
Aliases	KANSL2, C12orf41, NSL2, KAT8 regulatory NSL complex subunit 2
External IDs	OMIM: 615488; MGI: 1916862; GeneCards: KANSL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4CY2
Gene location (Human)
Chr.	Chromosome 12 (human)
End	48,682,238 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	98,432,145 bp
RNA expression pattern
	Top expressed in
	skeletal muscle tissue; ; bone marrow; ; gastrocnemius muscle; ; gonad; ; bone marrow cell; ; epithelium of colon; ; ganglionic eminence; ; granulocyte; ; ventricular zone; ; cerebellar hemisphere;
	Top expressed in
	ventricular zone; ; muscle of thigh; ; neural layer of retina; ; embryo; ; embryo; ; neural tube; ; esophagus; ; lip; ; yolk sac; ; spermatocyte;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	histone acetyltransferase activity (H4-K5 specific); histone acetyltransferase activity (H4-K16 specific); protein binding; histone acetyltransferase activity (H4-K8 specific);
Cellular component	histone acetyltransferase complex; nucleus; nucleoplasm; cytosol; plasma membrane; actin cytoskeleton; NSL complex;
Biological process	histone H4-K16 acetylation; histone H4-K8 acetylation; histone H4-K5 acetylation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	54934
	69612
	ENSG00000139620
	ENSMUSG00000022992
	Q9H9L4
	Q8BQR4
	NM_017822
NM_001289437; NM_001289438; NM_001289439; NM_001289440; NM_133714;
	NM_001359827
	NP_060292
NP_001276366; NP_001276367; NP_001276368; NP_001276369; NP_598475;
	NP_001346756
	Wikidata
View/Edit Human	View/Edit Mouse

KAT8 regulatory NSL complex subunit 2 (KANSL2) also known as non-specific lethal 2 homolog (NSL2) is a protein that in humans is encoded by the KANSL2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000139620 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022992 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
↑ "Entrez Gene: C12orf41 chromosome 12 open reading frame 41".

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Mata X, Taourit S, Le Provost F (2004). "Putative FLJ20436 gene characterisation in goat. Observed ubiquitous expression in goat and transgenic mice allowed to restrict the location of an hypothesised insulator element". Gene. 321: 137–44. doi:10.1016/j.gene.2003.08.004. PMID 14637001.
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.

This article on a gene on human chromosome 12 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000139620 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022992 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: C12orf41 chromosome 12 open reading frame 41".

KAT8 regulatory NSL complex subunit 2

See also

References

Further reading