KCTD13 Protein-coding gene in the species Homo sapiens
KCTD13 Identifiers Aliases KCTD13 External IDs OMIM : 608947 ; MGI : 1923739 ; GeneCards : KCTD13 Gene location (Mouse ) Chr. Chromosome 7 (mouse) Band 7| 7 F3 Start 126,528,051 bp End 126,544,803 bp
RNA expression patternBgee Human Mouse (ortholog)Top expressed in right testis left testis nucleus accumbens anterior cingulate cortex right frontal lobe prefrontal cortex amygdala Region I of hippocampus proper caudate nucleus right hemisphere of cerebellum
Top expressed in primary visual cortex superior frontal gyrus subiculum zygote dentate gyrus dentate gyrus of hippocampal formation granule cell piriform cortex globus pallidus cingulate gyrus hippocampus proper
More reference expression data
BioGPS
Wikidata
BTB/POZ domain-containing protein KCTD13 is a protein that in humans is encoded by the KCTD13 gene .
Clinical relevance
Mutations in this gene have been associated to abnormalities in brain growth and behaviour.
References
1 2 3 GRCh38: Ensembl release 89: ENSG00000174943 – Ensembl , May 20171 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030685 – Ensembl , May 2017↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .1 2 He H, Tan CK, Downey KM, So AG (October 2001). "A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen" . Proceedings of the National Academy of Sciences of the United States of America . 98 (21): 11979– 84. Bibcode :2001PNAS...9811979H . doi :10.1073/pnas.221452098 PMC 59753 PMID 11593007 . ↑ "Entrez Gene: KCTD13 potassium channel tetramerisation domain containing 13" .↑ Arbogast T, Razaz P, Ellegood J, McKinstry SU, Erdin S, Currall B, et al. (May 2019). "Kctd13-deficient mice display short-term memory impairment and sex-dependent genetic interactions" . Human Molecular Genetics . 28 (9): 1474– 1486. doi :10.1093/hmg/ddy436 . PMC 6489413 PMID 30590535 .
Further reading
Kutsenko AS, Gizatullin RZ, Al-Amin AN, Wang F, Kvasha SM, Podowski RM, et al. (July 2002). "NotI flanking sequences: a tool for gene discovery and verification of the human genome" . Nucleic Acids Research . 30 (14): 3163– 70. doi :10.1093/nar/gkf428 . PMC 135748 PMID 12136098 . Zhou J, Hu X, Xiong X, Liu X, Liu Y, Ren K, et al. (March 2005). "Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen". Journal of Experimental Zoology A . 303 (3): 227– 40. Bibcode :2005JEZA..303..227Z . doi :10.1002/jez.a.150 . PMID 15726626 . Tomaru T, Satoh T, Yoshino S, Ishizuka T, Hashimoto K, Monden T, et al. (January 2006). "Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma" . Endocrinology . 147 (1): 377– 88. doi :10.1210/en.2005-0450 PMID 16239304 .
External links
PDBe-KB provides an overview of all the structure information available in the PDB for Human KCTD13
