Kokey at Ako

Earthlings

• Toni Gonzaga/Abby Bautista (young) as Princess Reyes / Jackie Reyes - Jackie is a survivor from a massacre plot against her family, an alien abduction, growing up without parents to provide her needs, and moving on with life with no memory of her real identity. Despite her traumatic past, Jackie is a positive thinker. She is a resourceful and determined news reporter with a special interest in paranormal and extraterrestrial activities. She is obsessed with retracing the events of the past—looking for any leads of alien movements, hoping to find possible indications of her parents’ whereabouts. And that vital lead may be Kokey. The role was originally given to Angel Locsin. Locsin was replaced by Gonzaga due to Locsin's commitment to Imortal.
• Vhong Navarro/ Kyle Balili (young)

• as Bruce Kho Reyes - Bruce used to be the boy who fell in love with the little rich girl with no memory. He is Jackie's best friend, confidante and companion in the search for her missing parents. The hard work and sacrifices he made paid off when his one great love accepted his proposal to be his wife. One day before the wedding, Bruce accepts a news coverage that leads to an unfortunate accident of stellar proportions. Bruce seems to get mad at Bam-Bam (Toribia's Daughter) and helping Jackie and Josa as Bam-Bam teases them.
• as Belat - See: Belat

• Melai Cantiveros/ Amy Nobleza (young) as Josa Reyes - Josa sees and does everything in a different way---odd but funny. She is Bruce's cousin, and Jackie's best friend and pseudo-sister. Her carefree attitude is refreshing, but would often lead to a lot of hilarious misadventures.
• Jason Francisco as Adonis - Adonis had been training as a cameraman for Channel Z for the last six years but can't get a promotion. When Bruce starts working for the station, Adonis becomes one of his good friends. Adonis eventually becomes Josa's love interest.
• Ms. Gloria Romero as Barbara Reyes - Madam Barbra is a sophisticated woman who owns a TV network, Z Broadcasting Company, as well as several companies. Her authority cannot be questioned, but behind her straightforward, stern and unyielding command is a grandmother longing to be reunited with her long-lost son and granddaughter.
• Mickey Ferriols as Annie Reyes - Annie is Barbara's adopted daughter. She is insecure and greedy so she planned to kill Jackie (Princess)'s family. When the years passed, she wants to get the company (Z Broadcasting Company), and she knew that Jackie is Princess. So, she used Lois, to pretend to be Princess Reyes, the long-lost granddaughter of Barbara, but all of her plans didn't work. In the last episode, after a fight with the Reyeses, she was trapped in a glass mirror and dies after the mirror shattered, destroying her in the process.
• Wendy Valdez as Lois Magsanoc - Jackie's rival to the heart of Bruce and she pretended to be Princess Reyes (which Annie planned) because of her ambition to be an actress. When the truth was known that she is not the real Princess because Barbara saw her mother, a crazy one. And instead of being mad, she helped Barbara's family, even Jackie.

Yekokans

• Kokey - Kokey returns to Planet Earth to find his missing sister before she unwittingly wreaks havoc on mankind. In his search for his furry sibling, Kokey gets to meet new friends and goes into another roller-coaster adventure ride of his life.
• Kekay - Kekay is Kokey's jealous furry little sister. She was born thinking she was disliked and unloved by her parents, and grew up envious over her brother's popularity not only in Planet Yekok but on Earth as well. Her sense of curiosity and misadventure sends her to an accidental journey to Earth.
• Umamay Kakay - Kokey and Kekay's mother.
• Tay Kokoy - Kokey and Kekay's father.

Kukurikabukans

• Mike Lloren as King Cone - King Cone is the ruthless ruler of planet Kukurikabu. Disobedience of his orders will mean death to any human or exile to outer space for Kukurikabukans.
• Joy Viado as Bebot - One of the three elders of the more than 350 children spawned by King Cone. They are ruthless and heartless as their father; very much enthusiastic in brewing plans to invade other planets, particularly Earth, to call their second home.
• Tess Antonio as Babet - One of the three elders of the more than 350 children spawned by King Cone. They are ruthless and heartless as their father; very much enthusiastic in brewing plans to invade other planets, particularly Earth, to call their second home.
• Francis Magundayao as Belat - Prince Belat is one of the thousands of King Cone's kids. He is affectionate and caring towards the human prisoners of his father, an unthinkable and forbidden behavior for children of royalty. The young prince is most especially attached to Dianne, whom he treated as his mother. Belat's attachment to Dianne drove him to invent a spaceship to send the human couple back to their home planet. As Belat attempts to fly his alien craft to Earth, an accident occurs leaving him trapped in Bruce's body.
• Empoy Marquez as Bubot - One of the three elders of the more than 350 children spawned by King Cone. They are ruthless and heartless as their father; very much enthusiastic in brewing plans to invade other planets, particularly Earth, to call their second home.