LUC7L2

LUC7L2

Identifiers

LUC7L2, CGI-74, LUC7B2, CGI-59, LUC7-like 2 pre-mRNA splicing factor, LUC7 like 2, pre-mRNA splicing factor

External IDs

OMIM: 613056; MGI: 2183260; GeneCards: LUC7L2

Gene location (Human)

Chr.	Chromosome 7 (human)

Band	7q34	Start	139,340,359 bp
Band	7q34	End	139,423,457 bp

Gene location (Mouse)

Chr.	Chromosome 6 (mouse)

Band	6\|6 B1	Start	38,551,334 bp
Band	6\|6 B1	End	38,609,470 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

sural nerve

left lobe of thyroid gland

right lobe of thyroid gland

right uterine tube

gastric mucosa

Achilles tendon

canal of the cervix

ventricular zone

left uterine tube

Descending thoracic aorta

Top expressed in

mammillary body

ventromedial nucleus

lateral septal nucleus

body of femur

aortic valve

anterior amygdaloid area

cerebellar vermis

lateral geniculate nucleus

ascending aorta

lobe of cerebellum

More reference expression data


More reference expression data

Gene ontology
Molecular function	enzyme binding protein binding mRNA binding RNA binding
Cellular component	U1 snRNP nuclear speck U2-type prespliceosome nucleus nucleoplasm
Biological process	mRNA splice site selection
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


51631


192196


ENSG00000146963


ENSMUSG00000029823


Q9Y383


Q7TNC4

RefSeq (mRNA)


NM_016019 NM_001244585 NM_001270643

NM_001170848 NM_001170849 NM_138680 NM_001311099 NM_001311100
NM_001331222 NM_001331223

RefSeq (protein)


NP_001231514 NP_001257572 NP_057103

NP_001164319 NP_001164320 NP_001298028 NP_001298029 NP_001318151
NP_001318152 NP_619621

Location (UCSC)

Chr 7: 139.34 – 139.42 Mb

Chr 6: 38.55 – 38.61 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Putative RNA-binding protein Luc7-like 2 is a protein that in humans is encoded by the LUC7L2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000146963 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029823 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of Novel Human Genes Evolutionarily Conserved in Caenorhabditis elegans by Comparative Proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.
↑ "Entrez Gene: LUC7L2 LUC7-like 2 (S. cerevisiae)".

Further reading

Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. Bibcode:2003Natur.424..157H. doi:10.1038/nature01782. PMID 12853948.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization". Curr. Biol. 14 (16): 1436–50. Bibcode:2004CBio...14.1436J. doi:10.1016/j.cub.2004.07.051. PMID 15324660. S2CID 2371325.
Goehler H, Lalowski M, Stelzl U, et al. (2004). "A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease". Mol. Cell. 15 (6): 853–65. doi:10.1016/j.molcel.2004.09.016. PMID 15383276.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. hdl:11858/00-001M-0000-0010-8592-0. PMID 16169070. S2CID 8235923.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

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