MPHOSPH10

MPHOSPH10
Identifiers
Aliases	MPHOSPH10, CT90, MPP10, MPP10P, PPP1R106, M-phase phosphoprotein 10
External IDs	OMIM: 605503; MGI: 1915223; GeneCards: MPHOSPH10
Gene location (Human)
Chr.	Chromosome 2 (human)
End	71,150,101 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	64,042,016 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; tendon of biceps brachii; ; endometrium; ; mucosa of esophagus; ; oral cavity; ; pars compacta; ; glutes; ; pericardium; ; hair follicle; ; mucosa of pharynx;
	Top expressed in
	genital tubercle; ; zygote; ; tail of embryo; ; secondary oocyte; ; primary oocyte; ; epiblast; ; primitive streak; ; fetal liver hematopoietic progenitor cell; ; morula; ; morula;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; RNA binding;
Cellular component	sno(s)RNA-containing ribonucleoprotein complex; small-subunit processome; Mpp10 complex; nucleolus; nucleus; chromosome; nucleoplasm;
Biological process	RNA splicing, via transesterification reactions; negative regulation of phosphatase activity; RNA processing; ribosome biogenesis; RNA splicing; rRNA processing; maturation of SSU-rRNA;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	10199
	67973
	ENSG00000124383
	ENSMUSG00000030521
	O00566
	Q810V0
	NM_005791
	NM_026483
	NP_005782
	NP_080759
	Wikidata
View/Edit Human	View/Edit Mouse

U3 small nucleolar ribonucleoprotein protein MPP10 is a protein that in humans is encoded by the MPHOSPH10 gene.

This gene encodes a protein that is phosphorylated during mitosis. The protein localizes to the nucleolus during interphase and to the chromosomes during M phase. The protein is thought to be part of the U3 small nucleolar ribonucleoprotein complex, which is involved in rRNA processing.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000124383 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030521 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell. 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
↑ Westendorf JM, Konstantinov KN, Wormsley S, Shu MD, Matsumoto-Taniura N, Pirollet F, Klier FG, Gerace L, Baserga SJ (Mar 1998). "M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component". Mol Biol Cell. 9 (2): 437–49. doi:10.1091/mbc.9.2.437. PMC 25272. PMID 9450966.
1 2 "Entrez Gene: MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)".

External links

MPHOSPH10 human gene location in the UCSC Genome Browser.
MPHOSPH10 human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000124383 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030521 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8885239-5] Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell. 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.

[pmid9450966-6] Westendorf JM, Konstantinov KN, Wormsley S, Shu MD, Matsumoto-Taniura N, Pirollet F, Klier FG, Gerace L, Baserga SJ (Mar 1998). "M Phase Phosphoprotein 10 Is a Human U3 Small Nucleolar Ribonucleoprotein Component". Mol Biol Cell. 9 (2): 437–49. doi:10.1091/mbc.9.2.437. PMC 25272. PMID 9450966.

[entrez-7] 1 2 "Entrez Gene: MPHOSPH10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)".

MPHOSPH10

References

Further reading

External links