Masameer

Main Characters

• Saltooh (Voiced by Malik Nejer): A distinctive man who has a long nose. He drives a pickup truck that he, Saad and Trad use to travel. He faces pressure from his mother, who wants him to get a job and start a family of his own.^{[citation needed]}
• Saad (Voiced by Malik Nejer): A man who acts foolish. A former child prodigy and alumnus of MIT, a series of accidents on his way home caused him to be the way he is. He struggles with speaking due to dysarthia and has yellow eyes due to viral hepatitis.^{[citation needed]}
• Trad (Voiced by Malik Nejer): is an anthropomorphic dog whose ancestors are wolves. He is sometimes seen leading the two men. In one episode, he was revealed to be a long-lost member of an aristocratic British family.^{[citation needed]}

Recurring Characters

• Dr. Adel: (Voiced by Malik Nejer) An overweight doctor.
• Dr. Nafea
• Dr. Barbain
• Hizam: (Voiced by Malik Nejer) is a wise man but has a history of reckless driving.
• Sisteen
• Bandar (Voiced by Abdulaziz Alshehri): A wealthy man who is depicted as an entrepreneur, a sheikh, the head of Bandar Contracting as seen in Outer Space Toilet and opened a restaurant named Pink Love Restaurants For Traditional Saudi Food in one episode. As a child, he had abusive parents who punished him for going outside by putting him in his room.
• Mane
• Aqeel
• Sweiket
• The Pixel
• Mani'
• Nafi'
• Shalash
• Abdul Jalil
• Rashed
• Sultan
• Awad
• Waseem
• Khalaf
• Muneer
• Mazen
• Abdullah
• Abu Fahd

Minor Characters

• Lion: An emaciated lion
• Reem: Rashed's sister
• Hessa: A chef who knows how to cook kabsa, she died after falling into a kabsa pot she was stirring.

The series features many fictional secondary characters, including friends, townspeople, coworkers, and others. Some episodes feature cameos from characters and public figures such as Mohammed Abdu, Abbadi Al-Johar, Fidel Castro, Ziad Rahbani, Hosni Mubarak, Mickey Mouse, and Popeye. Famous basketball player Dwyane Wade appeared in one episode, where he portrayed himself.^{[citation needed]}