He is First Chairman of the Scientific Society for Homeopathy (WissHom), founded in 2010, president of the Umbrella organization of Austrian Doctors for Holistic Medicine, since 2002 and since 1994 Vicepresident of the Doctors Association for Classical Homeopathy.
Homoeopathic research
A major interest of Frass is homeopathy. He has published several papers on this subject.
Article in the Oncologist
In 2020 Frass was the corresponding author of an article in the medical journal The Oncologist which concluded that additional homoeopathic treatment improves quality of life and survival rates in patients with non‐small cell lung cancer (NSCLC). The results of the article were discussed outside of academic circles, for example in the Wiener Zeitung. After criticism (for example from the Informationsnetzwerk Homöopathie), the Austrian Agency for Scientific Integrity (Österreichische Agentur für wissenschaftliche Integrität) concluded that the article contains data manipulation and forgery. The Oncologist released an expression of concern in 2022 and retracted the article in November 2025.
Airway
He has also published several papers investigating the influence of controlled mechanical ventilation on the release of atrial natriuretic peptide. Furthermore, Frass has investigated devices designed for securing the airway under emergency conditions. He has performed studies on a broad range of different alternate airways.
Invention
Rapid assessment and management of respiratory structure and function are imperative in emergency intubation. Endotracheal intubation remains the gold standard in airway maintenance. However, endotracheal intubation may be impossible due to difficult circumstances with respect to space and illumination or anatomy even for skilled physicians. Therefore, the need arises for an alternative. The Combitube was designed with this goal in mind.
Frass is the inventor of the Combitube, a twin lumen device designed for use in emergency situations and difficult airways. He has published several papers on this topic.
↑Frass, Michael; Watschinger, Bruno; Traindl, Otto; Popovic, Rainer; Podolsky, Andrea; Gisslinger, Heinz; Falger, Susanne; Goldin, Michel; Schuster, Ernst; Leithner, Christian (1993). "Atrial natriuretic peptide release in response to different positive end-expiratory pressure levels". Critical Care Medicine. 21 (3): 343–347. doi:10.1097/00003246-199303000-00009. PMID8440102.
↑Frass, Michael; Popovic, Rainer; Hartter, Engelbert; Auinger, Christian; Woloszczuk, Wolfgang; Leithner, Christian (1988). "Atrial natriuretic peptide decrease during spontaneous breathing with continuous positive airway pressure in volume-expanded healthy volunteers". Critical Care Medicine. 16 (9): 831–835. doi:10.1097/00003246-198809000-00002. PMID2969791.
↑Leithner, Christian; Frass, Michael; Pacher, Richard; Hartter, Engelbert; Pesl, Harald; Woloszczuk, Wolfgang (1987). "Mechanical ventilation with positive end-expiratory pressure decreases release of alpha-atrial natriuretic peptide". Critical Care Medicine. 15 (5): 484–488. doi:10.1097/00003246-198705000-00005. PMID2952461.
↑Rabitsch, Werner; Köstler, Wolfgang J.; Burgmann, Heinz; Krafft, Peter; Frass, Michael (2005). "Recommendation of the Minimal Volume Technique to Avoid Tongue Engorgement with Prolonged Use of the Esophageal-Tracheal Combitube". Annals of Emergency Medicine. 45 (5): 565–566. doi:10.1016/j.annemergmed.2004.11.031. PMID15855963.
↑Schaumann, Nikolaus; Lorenz, Veit; Schellongowski, Peter; Staudinger, Thomas; Locker, Gottfried J.; Burgmann, Heinz; Pikula, Branko; Hofbauer, Roland; Schuster, Ernst; Frass, Michael (2005). "Evaluation of Seldinger Technique Emergency Cricothyroidotomy versus Standard Surgical Cricothyroidotomy in 200 Cadavers". Anesthesiology. 102 (1): 7–11. doi:10.1097/00000542-200501000-00005. PMID15618780.
↑Rabitsch, W.; Köstler, W. J.; Fiebiger, W.; Dielacher, C.; Losert, H.; Sherif, C.; Staudinger, T.; Seper, E.; Koller, W.; Daxböck, F.; Schuster, E.; Knöbl, P.; Burgmann, H.; Frass, M. (2004). "Closed suctioning system reduces cross-contamination between bronchial system and gastric juices". Anesthesia and Analgesia. 99 (3): 886–92, table of contents. doi:10.1213/01.ANE.0000143353.85428.39 (inactive 12 July 2025). PMID15333426.{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)
↑Knapp, Sylvia; Kofler, Julia; Stoiser, Brigitte; Thalhammer, Florian; Burgmann, Heinz; Posch, Martin; Hofbauer, Roland; Stanzel, Margit; Frass, Michael (1999). "The Assessment of Four Different Methods to Verify Tracheal Tube Placement in the Critical Care Setting". Anesthesia & Analgesia. 88 (4): 766–770. doi:10.1097/00000539-199904000-00016. PMID10195521.
↑Ruetzler, Kurt; Roessler, Bernhard; Potura, Lukasz; Priemayr, Anita; Robak, Oliver; Schuster, Ernst; Frass, Michael (2011). "Performance and skill retention of intubation by paramedics using seven different airway devices—A manikin study". Resuscitation. 82 (5): 593–597. doi:10.1016/j.resuscitation.2011.01.008. PMID21353364.
↑Robak, Oliver; Leonardelli, Marco; Zedtwitz-Liebenstein, Konstantin; Rützler, Kurt; Schuster, Ernst; Vaida, Sonia; Salem, Ramez; Frass, Michael (2012). "Feasibility and speed of insertion of seven supraglottic airway devices under simulated airway conditions". CJEM. 14 (6): 330–334. doi:10.2310/8000.2012.120658. PMID23131479.
↑Biebuyck, Jullen F.; Benumof, Jonathan L. (1991). "Management of the Difficult Adult Airway with Special Emphasis on Awake Tracheal Intubation". Anesthesiology. 75 (6): 1087–1110. doi:10.1097/00000542-199112000-00021. PMID1824555.
↑Ochs, Mel; Vilke, Gary M.; Chan, Theodore C.; Moats, Thomas; Buchanan, Jean (2000). "S Uccessful P Rehospital a Irway M Anagement by Emt-D S U Sing the C Ombitube". Prehospital Emergency Care. 4 (4): 333–337. doi:10.1080/10903120090941065. PMID11045413.
↑Lefrançois, Daniel P.; Dufour, Daniel G. (2002). "Use of the esophageal tracheal combitube™ by basic emergency medical technicians". Resuscitation. 52 (1): 77–83. doi:10.1016/s0300-9572(01)00441-5. PMID11801352.
↑Frass M, Salem MR, Vaida S, Hagberg CA. Esophageal-tracheal double-lumen airways: the Combitube and Easytube. Benumof and Hagberg's Airway Management, 3rd Edition, 2013, Publisher Saunders.
↑Frass, Michael; Rodler, Suzanne; Frenzer, Reinhard; Ilias, Wilfried; Leithner, Christian; Lackner, Franz (1989). "Esophageal Tracheal Combitube, Endotracheal Airway, and Mask". The Journal of Trauma: Injury, Infection, and Critical Care. 29 (11): 1476–1479. doi:10.1097/00005373-198911000-00004. PMID2585558.