Oxford Nanopore Technologies

Oxford Nanopore Technologies plc
Oxford Nanopore Technologies plc
Type	Public limited company
Traded as	LSE: ONT; FTSE 250 component;
ISIN	GB00BP6S8Z30
Industry	Nanopore sequencing
Founded	2005; 21 years ago
Founders	Hagan Bayley; Gordon Sanghera; Spike Willcocks;
Headquarters	Oxford Science Park, Oxford, United Kingdom
Key people	Duncan Tatton-Brown (Chair); Francis Van Parys (CEO);
Revenue	£223.9 million (2025)
Operating income	£(155.3) million (2025)
Net income	£(145.2) million (2025)
Website	nanoporetech.com

Oxford Nanopore Technologies plc is a UK-based company which develops and sells nanopore-based molecular sensing technology for the real-time analysis of DNA and RNA. Its platform includes sequencing devices, consumables and software used across research, applied and clinical markets. It is listed on the London Stock Exchange and is a constituent of the FTSE 250 Index.

History

The company was founded in 2005 as a spin-out from the University of Oxford by Hagan Bayley, Gordon Sanghera, and Spike Willcocks, with seed funding from the IP Group. The company made an initial public offering on the London Stock Exchange on 30 September 2021, under the ticker ONT.

In March 2016 the company announced a chemistry upgrade to its nanopore sequencing product 'R9', using a protein nanopore in collaboration with the laboratory of Han Remaut (VIB/Vrije Universiteit Brussel). The company stated in a webcast that R9 is designed to improve error rates and yield.

In December 2025, the company announced that Francis Van Parys would succeed Gordon Sanghera as CEO. Prior to joining Oxford Nanopore, he was President and CEO of Radiometer and held senior leadership roles at Cytiva and GE Healthcare.

Products

The main products of Oxford Nanopore are:

MinION: this harmonica-sized portable protein nanopore sequencing USB device has been commercially available since May 2015.
GridION: this desktop device has been commercially available since March 2017. The device processes up to five MinION flow cells and enables generation of up to 100 Gb of data per run.
PromethION: a desktop device for sequencing of native DNA or RNA samples. The device contains channels for 144,000 nanopores (in comparison to MinION’s 512) and delivers up to 290 Gb of data per flow cell.
PromethION 24: this device is a nanopore sequencing platform released in 2019 for DNA and RNA sequencing projects. It 24 flow cells which can be run independently.
EPI2ME: a procut for customers with limited computational experience to process data without high-performance computing resources and programming expertise.

These products are intended to be used for the analysis of DNA, RNA, proteins and small molecules with a range of applications in personalized medicine, Agricultural science and scientific research.

References

1 2 3 "Annual Results for year ended 31 December 2025". Oxford Nanopore Technologies. Retrieved 2 March 2026.
↑ Eisenstein, M. (2012). "Oxford Nanopore announcement sets sequencing sector abuzz". Nature Biotechnology. 30 (4): 295–6. Bibcode:2012NatBi..30..295E. doi:10.1038/nbt0412-295. PMID 22491260. S2CID 205267199.
↑ Engineer, The (8 July 2026). "Gene sequencing pioneer Oxford Nanopore Technologies wins 2026 MacRobert Award". The Engineer. Retrieved 24 July 2026.
↑ Eisenstein, Michael (10 April 2012). "Oxford Nanopore announcement sets sequencing sector abuzz". Nature Biotechnology. 30 (4): 295–296. doi:10.1038/nbt0412-295. ISSN 1087-0156.
↑ Pugh, Jonathan (2023), Arakawa, Kazuharu (ed.), "The Current State of Nanopore Sequencing", Nanopore Sequencing, vol. 2632, New York, NY: Springer US, pp. 3–14, doi:10.1007/978-1-0716-2996-3_1, ISBN 978-1-0716-2995-6, retrieved 18 August 2026{{citation}}: CS1 maint: work parameter with ISBN (link)
↑ Si, Hua-Qi; Wang, Peng; Long, Fei; Zhong, Wei; Meng, Yuan-Dong; Rong, Yuan; Meng, Xiang-Yu; Wang, Fu-Bing (29 November 2024). "Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications". Molecular Cancer. 23 (1). doi:10.1186/s12943-024-02178-6. ISSN 1476-4598. PMC 11605934. PMID 39614371.
↑ Loman, N. J.; Quinlan, A. R. (2014). "Poretools: A toolkit for analyzing nanopore sequence data". Bioinformatics. 30 (23): 3399–401. doi:10.1093/bioinformatics/btu555. PMC 4296151. PMID 25143291.
↑ "FTSE UK Index Series Quarterly Review December 2024". FTSE Russell. 4 December 2024. Retrieved 20 December 2024.
↑ "BAYLEY, Prof. (John) Hagan (Pryce)". Who's Who. Vol. 2015 (online edition via Oxford University Press ed.). A & C Black. (Subscription or UK public library membership required.)
↑ "DNA sequencing: The hole story". The Economist. London. 16 October 2008. Retrieved 19 October 2014.
↑ "London Stock Exchange welcomes Oxford Nanopore Technologies plc to the Main Market". 11 October 2021.
↑ "VIB announces collaboration with Oxford Nanopore Technologies on new DNA sequencing nanopore". Retrieved 9 May 2016.
↑ "No thanks, I've already got one". YouTube. 8 March 2016. Retrieved 9 May 2016.
1 2 "Appointment of Francis Van Parys as Chief Executive Officer". Business Wire. 8 December 2025. Retrieved 24 July 2026.{{cite web}}: CS1 maint: url-status (link)
↑ Mikheyev, A. S.; Tin, M. M. Y. (2014). "A first look at the Oxford Nanopore MinION sequencer". Molecular Ecology Resources. 14 (6): 1097–102. Bibcode:2014MolER..14.1097M. doi:10.1111/1755-0998.12324. PMID 25187008. S2CID 3674911.
↑ Check Hayden, E. (2014). "Data from pocket-sized genome sequencer unveiled". Nature. doi:10.1038/nature.2014.14724.
↑ Check Hayden, E. (2015). "Pint-sized DNA sequencer impresses first users". Nature. 521 (7550): 15–6. Bibcode:2015Natur.521...15C. doi:10.1038/521015a. PMID 25951262.
↑ "IP Group PLC – Portfolio company Oxford Nanopore announces £70m fundraising – IP Group PLC". Archived from the original on 21 November 2015. Retrieved 20 November 2015.
↑ "Oxford Nanopore Launches GridIon X5 Nanopore Sequencer, Details Product Improvements". GenomeWeb. Retrieved 6 July 2017.
↑ "GridION X5". nanoporetech.com. Retrieved 6 July 2017.
↑ Faucher, Lisa (11 March 2022). "PromethION: Flexible, large-scale, direct DNA and RNA sequencing". BioTechniques. Retrieved 24 July 2026.
↑ "Specifications - Community - Oxford Nanopore Technologies". Archived from the original on 1 June 2016. Retrieved 20 November 2015.
↑ "Oxford Nanopore Technologies: Oxford Nanopore launches PromethION 2 Integrated into open early access". FinanzNachrichten.de (in German). Retrieved 24 July 2026.
↑ "Oxford Nanopore PromethION 24/48". genohub.com. Retrieved 18 August 2026.
↑ "PromethION 24: sequencing to the power of 24". Oxford Nanopore Technologies. Retrieved 18 August 2026.
↑ Quiñones-Sanchez, Carlos L.; Bilbao-Del Valle, Jan L.; Urdaneta-Colon, Miguel A.; Santiago-Rodriguez, Tasha M.; Rodriguez-Fernandez, Imilce A. (15 November 2025), Optimizing Tissue Lysis and DNA Extraction Protocols to Enhance Bacterial Diversity Profiling in the Drosophila melanogaster Gut Microbiome, doi:10.1101/2025.11.15.688634, PMC 12642230, PMID 41292709, retrieved 18 August 2026
↑ Oxford Nanopore Technologies (5 June 2026). EPI2ME evolution – latest developments and the road ahead. Retrieved 25 July 2026 – via YouTube.
↑ Check Hayden, Erika (2012). "Nanopore genome sequencer makes its debut". Nature. doi:10.1038/nature.2012.10051. ISSN 1744-7933.

External links

Oxford Nanopore Technologies Website

[results-1] 1 2 3 "Annual Results for year ended 31 December 2025". Oxford Nanopore Technologies. Retrieved 2 March 2026.

[2] Eisenstein, M. (2012). "Oxford Nanopore announcement sets sequencing sector abuzz". Nature Biotechnology. 30 (4): 295–6. Bibcode:2012NatBi..30..295E. doi:10.1038/nbt0412-295. PMID 22491260. S2CID 205267199.

[3] Engineer, The (8 July 2026). "Gene sequencing pioneer Oxford Nanopore Technologies wins 2026 MacRobert Award". The Engineer. Retrieved 24 July 2026.

[4] Eisenstein, Michael (10 April 2012). "Oxford Nanopore announcement sets sequencing sector abuzz". Nature Biotechnology. 30 (4): 295–296. doi:10.1038/nbt0412-295. ISSN 1087-0156.

[5] Pugh, Jonathan (2023), Arakawa, Kazuharu (ed.), "The Current State of Nanopore Sequencing", Nanopore Sequencing, vol. 2632, New York, NY: Springer US, pp. 3–14, doi:10.1007/978-1-0716-2996-3_1, ISBN 978-1-0716-2995-6, retrieved 18 August 2026{{citation}}: CS1 maint: work parameter with ISBN (link)

[6] Si, Hua-Qi; Wang, Peng; Long, Fei; Zhong, Wei; Meng, Yuan-Dong; Rong, Yuan; Meng, Xiang-Yu; Wang, Fu-Bing (29 November 2024). "Cancer liquid biopsies by Oxford Nanopore Technologies sequencing of cell-free DNA: from basic research to clinical applications". Molecular Cancer. 23 (1). doi:10.1186/s12943-024-02178-6. ISSN 1476-4598. PMC 11605934. PMID 39614371.

[7] Loman, N. J.; Quinlan, A. R. (2014). "Poretools: A toolkit for analyzing nanopore sequence data". Bioinformatics. 30 (23): 3399–401. doi:10.1093/bioinformatics/btu555. PMC 4296151. PMID 25143291.

[8] "FTSE UK Index Series Quarterly Review December 2024". FTSE Russell. 4 December 2024. Retrieved 20 December 2024.

[haganswho-9] "BAYLEY, Prof. (John) Hagan (Pryce)". Who's Who. Vol. 2015 (online edition via Oxford University Press ed.). A & C Black. (Subscription or UK public library membership required.)

[economist-10] "DNA sequencing: The hole story". The Economist. London. 16 October 2008. Retrieved 19 October 2014.

[11] "London Stock Exchange welcomes Oxford Nanopore Technologies plc to the Main Market". 11 October 2021.

[12] "VIB announces collaboration with Oxford Nanopore Technologies on new DNA sequencing nanopore". Retrieved 9 May 2016.

[13] "No thanks, I've already got one". YouTube. 8 March 2016. Retrieved 9 May 2016.

[:0-14] 1 2 "Appointment of Francis Van Parys as Chief Executive Officer". Business Wire. 8 December 2025. Retrieved 24 July 2026.{{cite web}}: CS1 maint: url-status (link)

[minion-15] Mikheyev, A. S.; Tin, M. M. Y. (2014). "A first look at the Oxford Nanopore MinION sequencer". Molecular Ecology Resources. 14 (6): 1097–102. Bibcode:2014MolER..14.1097M. doi:10.1111/1755-0998.12324. PMID 25187008. S2CID 3674911.

[pocket-16] Check Hayden, E. (2014). "Data from pocket-sized genome sequencer unveiled". Nature. doi:10.1038/nature.2014.14724.

[17] Check Hayden, E. (2015). "Pint-sized DNA sequencer impresses first users". Nature. 521 (7550): 15–6. Bibcode:2015Natur.521...15C. doi:10.1038/521015a. PMID 25951262.

[18] "IP Group PLC – Portfolio company Oxford Nanopore announces £70m fundraising – IP Group PLC". Archived from the original on 21 November 2015. Retrieved 20 November 2015.

[19] "Oxford Nanopore Launches GridIon X5 Nanopore Sequencer, Details Product Improvements". GenomeWeb. Retrieved 6 July 2017.

[20] "GridION X5". nanoporetech.com. Retrieved 6 July 2017.

[21] Faucher, Lisa (11 March 2022). "PromethION: Flexible, large-scale, direct DNA and RNA sequencing". BioTechniques. Retrieved 24 July 2026.

[22] "Specifications - Community - Oxford Nanopore Technologies". Archived from the original on 1 June 2016. Retrieved 20 November 2015.

[23] "Oxford Nanopore Technologies: Oxford Nanopore launches PromethION 2 Integrated into open early access". FinanzNachrichten.de (in German). Retrieved 24 July 2026.

[24] "Oxford Nanopore PromethION 24/48". genohub.com. Retrieved 18 August 2026.

[25] "PromethION 24: sequencing to the power of 24". Oxford Nanopore Technologies. Retrieved 18 August 2026.

[26] Quiñones-Sanchez, Carlos L.; Bilbao-Del Valle, Jan L.; Urdaneta-Colon, Miguel A.; Santiago-Rodriguez, Tasha M.; Rodriguez-Fernandez, Imilce A. (15 November 2025), Optimizing Tissue Lysis and DNA Extraction Protocols to Enhance Bacterial Diversity Profiling in the Drosophila melanogaster Gut Microbiome, doi:10.1101/2025.11.15.688634, PMC 12642230, PMID 41292709, retrieved 18 August 2026

[27] Oxford Nanopore Technologies (5 June 2026). EPI2ME evolution – latest developments and the road ahead. Retrieved 25 July 2026 – via YouTube.

[Check_Hayden2012-28] Check Hayden, Erika (2012). "Nanopore genome sequencer makes its debut". Nature. doi:10.1038/nature.2012.10051. ISSN 1744-7933.