Nephronectin

NPNT
Identifiers
Aliases	NPNT, EGFL6L, POEM, nephronectin
External IDs	OMIM: 610306; MGI: 2148811; GeneCards: NPNT
Gene location (Human)
Chr.	Chromosome 4 (human)
End	106,004,027 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	132,656,052 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; right lung; ; jejunal mucosa; ; right coronary artery; ; Descending thoracic aorta; ; ascending aorta; ; lower lobe of lung; ; upper lobe of lung; ; upper lobe of left lung;
	Top expressed in
	ascending aorta; ; epithelium of lens; ; aortic valve; ; left lung lobe; ; tunica media of zone of aorta; ; right lung lobe; ; calvaria; ; medullary collecting duct; ; molar; ; efferent ductule;
	More reference expression data
	n/a
Gene ontology
Molecular function	calcium ion binding; integrin binding; extracellular matrix structural constituent;
Cellular component	membrane; smooth muscle contractile fiber; extracellular matrix; integrin alpha8-beta1 complex; extracellular region; basement membrane; extracellular exosome; extracellular space; collagen-containing extracellular matrix;
Biological process	positive regulation of transforming growth factor beta receptor signaling pathway; cell differentiation; ureteric bud development; establishment of protein localization; cellular response to tumor necrosis factor; extracellular matrix organization; cell-cell adhesion mediated by integrin; multicellular organism development; branching involved in ureteric bud morphogenesis; positive regulation of osteoblast differentiation; cell adhesion; pilomotor reflex; positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation; positive regulation of alkaline phosphatase activity; positive regulation of ERK1 and ERK2 cascade; cell-matrix adhesion; positive regulation of smooth muscle contraction; positive regulation of cell-substrate adhesion;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	255743
	114249
	ENSG00000168743
	ENSMUSG00000040998
	Q6UXI9
	Q91V88
NM_001033047; NM_001184690; NM_001184691; NM_001184692; NM_001184693;
	NM_198278
	NM_001029836; NM_001287101; NM_001287102; NM_001287103; NM_033525
	NP_001028219; NP_001171619; NP_001171620; NP_001171621; NP_001171622
	NP_001025007; NP_001274030; NP_001274031; NP_001274032; NP_277060
	Wikidata
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