Nucleoporin 160

NUP160
Identifiers
Aliases	NUP160, nucleoporin 160, Nup160, 160kDa, 2810011M03Rik, AA414952, AU020188, Gtl-13, Gtl1-13, Gtl13, mKIAA0197, NPHS19
External IDs	OMIM: 607614; MGI: 1926227; GeneCards: NUP160
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5A9Q
Gene location (Human)
Chr.	Chromosome 11 (human)
End	47,848,555 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	90,566,672 bp
RNA expression pattern
	Top expressed in
	oocyte; ; mucosa of paranasal sinus; ; secondary oocyte; ; ganglionic eminence; ; ventricular zone; ; germinal epithelium; ; left ovary; ; right ovary; ; endometrium; ; epithelium of colon;
	Top expressed in
	spermatid; ; epiblast; ; tail of embryo; ; zygote; ; secondary oocyte; ; mandibular prominence; ; maxillary prominence; ; genital tubercle; ; primary oocyte; ; abdominal wall;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; structural constituent of nuclear pore;
Cellular component	cytosol; nuclear envelope; nuclear pore; nuclear pore outer ring; nucleus; kinetochore; host cell;
Biological process	mRNA transport; protein transport; viral process; mRNA export from nucleus; regulation of glycolytic process; tRNA export from nucleus; protein sumoylation; viral transcription; regulation of gene silencing by miRNA; nephron development; intracellular transport of virus; regulation of cellular response to heat;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	23279
	59015
	ENSG00000030066
	ENSMUSG00000051329
	Q12769
	Q9Z0W3
	NM_015231; NM_001318399
	NM_021512
	NP_001305328; NP_056046
	NP_067487
	Wikidata
View/Edit Human	View/Edit Mouse

Nucleoporin 160 (Nup160) is a protein that in humans is encoded by the NUP160 gene.

NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000030066 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051329 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ (Oct 2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export". J Cell Biol. 155 (3): 339–54. doi:10.1083/jcb.200108007. PMC 2150853. PMID 11684705.
1 2 "Entrez Gene: NUP160 nucleoporin 160kDa".

Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
Belgareh N, Rabut G, Baï SW, et al. (2001). "An evolutionarily conserved NPC subcomplex, which redistributes in part to kinetochores in mammalian cells". J. Cell Biol. 154 (6): 1147–60. doi:10.1083/jcb.200101081. PMC 2150808. PMID 11564755.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Loïodice I, Alves A, Rabut G, et al. (2005). "The entire Nup107-160 complex, including three new members, is targeted as one entity to kinetochores in mitosis". Mol. Biol. Cell. 15 (7): 3333–44. doi:10.1091/mbc.E03-12-0878. PMC 452587. PMID 15146057.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Orjalo AV, Arnaoutov A, Shen Z, et al. (2006). "The Nup107-160 nucleoporin complex is required for correct bipolar spindle assembly". Mol. Biol. Cell. 17 (9): 3806–18. doi:10.1091/mbc.E05-11-1061. PMC 1593160. PMID 16807356.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Glavy JS, Krutchinsky AN, Cristea IM, et al. (2007). "Cell-cycle-dependent phosphorylation of the nuclear pore Nup107-160 subcomplex". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 3811–6. Bibcode:2007PNAS..104.3811G. doi:10.1073/pnas.0700058104. PMC 1820666. PMID 17360435.
Zuccolo M, Alves A, Galy V, et al. (2007). "The human Nup107-160 nuclear pore subcomplex contributes to proper kinetochore functions". EMBO J. 26 (7): 1853–64. doi:10.1038/sj.emboj.7601642. PMC 1847668. PMID 17363900.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Nuclear pore complex protein Nup160

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000030066 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000051329 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11684705-5] Vasu S, Shah S, Orjalo A, Park M, Fischer WH, Forbes DJ (Oct 2001). "Novel vertebrate nucleoporins Nup133 and Nup160 play a role in mRNA export". J Cell Biol. 155 (3): 339–54. doi:10.1083/jcb.200108007. PMC 2150853. PMID 11684705.

[entrez-6] 1 2 "Entrez Gene: NUP160 nucleoporin 160kDa".

v t e Autoantigens
Dehydrogenase	Branched-chain alpha-keto acid dehydrogenase complex Oxoglutarate dehydrogenase Pyruvate dehydrogenase
Transglutaminase	Epidermal transglutaminase Tissue transglutaminase
Nucleoporins	NUP35 NUP37 NUP43 NUP50 NUP54 NUP62 NUP85 NUP88 NUP93 NUP98 NUP107 NUP133 NUP153 NUP155 NUP160 NUP188 NUP205 NUP210 NUP214
Other	Acetylcholine receptor Actin Apolipoprotein H Cardiolipin Centromere Filaggrin (Citrullinate) Gangliosides Sp100 nuclear antigen Thrombin Topoisomerase

Nucleoporin 160

References

Further reading

External links