NEO1

NEO1
Identifiers
Aliases	NEO1, IGDCC2, NGN, NTN1R2, neogenin 1
External IDs	OMIM: 601907; MGI: 1097159; GeneCards: NEO1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X5F, 1X5G, 1X5H, 1X5I, 1X5J, 1X5K, 3P4L, 4UI2
Gene location (Human)
Chr.	Chromosome 15 (human)
End	73,305,205 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	58,943,724 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; internal globus pallidus; ; inferior ganglion of vagus nerve; ; rectum; ; epithelium of colon; ; subthalamic nucleus; ; corpus callosum; ; ventral tegmental area; ; superior vestibular nucleus; ; pylorus;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; epithelium of lens; ; renal corpuscle; ; medullary collecting duct; ; substantia nigra; ; ciliary body; ; ascending aorta; ; Rostral migratory stream; ; aortic valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	co-receptor binding; protein binding; signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane protein complex; plasma membrane; Golgi apparatus; integral component of plasma membrane; membrane; nucleoplasm;
Biological process	positive regulation of BMP signaling pathway; iron ion homeostasis; cell adhesion; nervous system development; axon guidance; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	4756
	18007
	ENSG00000067141
	ENSMUSG00000032340
	Q92859
	P97798
	NM_001172623; NM_001172624; NM_002499
	NM_001042752; NM_008684
	NP_001166094; NP_001166095; NP_002490
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Neogenin is a protein that in humans is encoded by the NEO1 gene.

Interactions

NEO1 has been shown to interact with PTK2. Also Neogenin receptor is pointed as a component of the mechanisms that determine skeletal cell fusion via RGMa (repulsive guidance molecule a) binding.