ODAD4

ODAD4
Identifiers
Aliases	ODAD4, tetratricopeptide repeat domain 25, TTC25, outer dynein arm docking complex subunit 4
External IDs	OMIM: 617095; MGI: 1921657; GeneCards: ODAD4
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,966,503 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	100,463,394 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; bronchial epithelial cell; ; sperm; ; pancreatic ductal cell; ; left testis; ; right testis; ; olfactory zone of nasal mucosa; ; mucosa of paranasal sinus; ; endothelial cell; ; tendon of biceps brachii;
	Top expressed in
	seminiferous tubule; ; spermatid; ; spermatocyte; ; otolith organ; ; utricle; ; olfactory epithelium; ; Epithelium of choroid plexus; ; neural layer of retina; ; salivary gland; ; morula;
	More reference expression data
	n/a
Orthologs
Databases	NCBI: entry; OMA: entry
	83538
	74407
	ENSG00000204815
	ENSMUSG00000006784
	Q96NG3
	Q9D4B2
	NM_031421; NM_001350319
	NM_028918; NM_001363174
	NP_113609; NP_001337248
	NP_083194; NP_001350103
	Wikidata
View/Edit Human	View/Edit Mouse

Outer dynein arm-docking complex subunit 4 is a protein that in humans is encoded by the ODAD4 gene (previously TTC25). This protein is part of a protein complex that is involved in the docking of the outer dynein arm to cilia. Pathogenic mutations are associated with the disorder primary ciliary dyskinesia 35.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000204815 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000006784 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 3 "Entrez Gene: ODAD4 outer dynein arm docking complex subunit 4".

Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

This article on a gene on human chromosome 17 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000204815 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000006784 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 3 "Entrez Gene: ODAD4 outer dynein arm docking complex subunit 4".

ODAD4

References

Further reading