Oolonghomobisflavan B

Oolonghomobisflavan B
Names
IUPAC name
[8-[[5,7-Dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-6-yl]methyl]-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
Identifiers
3D model (JSmol)
  • C1C(C(OC2=C1C(=CC(=C2CC3=C(C4=C(C=C3O)OC(C(C4)OC(=O)C5=CC(=C(C(=C5)O)O)O)C6=CC(=C(C(=C6)O)O)O)O)O)O)C7=CC(=C(C(=C7)O)O)O)OC(=O)C8=CC(=C(C(=C8)O)O)O
Properties
C45H36O22
Molar mass 928.761 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Oolonghomobisflavan B is an oolong tea polymerized polyphenol that can boost lipid metabolism-related gene expression. It can suppress p38 MAPK activation.

References

  1. ↑ Marugame, Yuki; Yoshitomi, Ren; Yang, Lin-Yun; Lin, Ting-An; Lee, Kwanwoo; Kumazoe, Motofumi; Fujimura, Yoshinori; Tachibana, Hirofumi (2025). "Regulatory Effect of Oolonghomobisflavan B on the Expression of miRNAs Secreted by Intestinal Cells". ACS Food Science & Technology. 5 (8): 3047–3053. Bibcode:2025AFST....5.3047M. doi:10.1021/acsfoodscitech.5c00322.
  2. ↑ Lim, Soomin; Kim, Tae Hoon; Ihn, Hye Jung; Lim, Jiwon; Kim, Gi-Young; Choi, Yung Hyun; Bae, Jong-Sup; Jung, Jae-Chang; Shin, Hong-In; Kim, Jung-Eun; Park, Eui Kyun (2020). "Inhibitory effect of oolonghomobisflavan B on osteoclastogenesis by suppressing p38 MAPK activation". Bioorganic & Medicinal Chemistry Letters. 30 (18) 127429. doi:10.1016/j.bmcl.2020.127429. PMID 32731089.