PAN3

PAN3
Identifiers
Aliases	PAN3, PAN3 poly(A) specific ribonuclease subunit, poly(A) specific ribonuclease subunit PAN3
External IDs	OMIM: 617448; MGI: 1919837; GeneCards: PAN3
Gene location (Human)
Chr.	Chromosome 13 (human)
End	28,295,335 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	147,485,312 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; secondary oocyte; ; thymus; ; trabecular bone; ; epithelium of nasopharynx; ; cerebellar vermis; ; skin of arm; ; mucosa of ileum; ; germinal epithelium; ; corpus epididymis;
	Top expressed in
	zygote; ; secondary oocyte; ; genital tubercle; ; tail of embryo; ; spermatid; ; thymus; ; cerebellar cortex; ; spermatocyte; ; lobe of cerebellum; ; neural layer of retina;
	More reference expression data
	n/a
Gene ontology
Molecular function	poly(A)-specific ribonuclease activity; protein kinase activity; nucleotide binding; protein binding; ATP binding; metal ion binding; RNA binding;
Cellular component	cytoplasm; cytosol; PAN complex; P-body;
Biological process	protein phosphorylation; protein targeting; mRNA processing; RNA phosphodiester bond hydrolysis, exonucleolytic; nuclear-transcribed mRNA poly(A) tail shortening; deadenylation-dependent decapping of nuclear-transcribed mRNA; positive regulation of cytoplasmic mRNA processing body assembly; nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	255967
	72587
	ENSG00000152520
	ENSMUSG00000029647
	Q58A45
	Q640Q5
	NM_175854
	NM_028291; NM_001359433
	NP_787050
	NP_082567; NP_001346362
	Wikidata
View/Edit Human	View/Edit Mouse

PAN3 poly(A) specific ribonuclease subunit is a protein that in humans is encoded by the PAN3 gene. PAN3 is part of the PAN deadenylation complex involved in shortening mRNA.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000152520 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029647 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "Entrez Gene: PAN3 poly(A) specific ribonuclease subunit". Retrieved 2016-09-27.

PAN3

See also

References

Further reading