PDF (gene)

PDF
Identifiers
AliasesPDF, peptide deformylase (mitochondrial), peptide deformylase, mitochondrial
External IDsMGI: 1915273; GeneCards: PDF
Available structures
PDBOrtholog search: PDBe RCSB
Enzyme activity
EC #BRENDAExPASyKEGGMetaCyc
3.5.1.88↗↗↗↗
Orthologs
DatabasesNCBI: entry; OMA: entry
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_022341

NM_026513

RefSeq (protein)

NP_071736

NP_080789

Location (UCSC)Chr 16: 69.33 – 69.33 MbChr 8: 107.77 – 107.78 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Peptide deformylase, mitochondrial is an enzyme that in humans is encoded by the PDF gene.

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000258429 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000078931 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Giglione C, Serero A, Pierre M, Boisson B, Meinnel T (Nov 2000). "Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms". EMBO J. 19 (21): 5916–29. doi:10.1093/emboj/19.21.5916. PMC 305796. PMID 11060042.
  6. ↑ Lee MD, She Y, Soskis MJ, Borella CP, Gardner JR, Hayes PA, Dy BM, Heaney ML, Philips MR, Bornmann WG, Sirotnak FM, Scheinberg DA (Oct 2004). "Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics". J Clin Invest. 114 (8): 1107–16. doi:10.1172/JCI22269. PMC 522256. PMID 15489958.
  7. ↑ "Entrez Gene: PDF peptide deformylase (mitochondrial)".

Further reading