PKD1L1

PKD1L1
Identifiers
Aliases	PKD1L1, PRO19563, polycystin 1 like 1, transient receptor potential channel interacting, HTX8
External IDs	OMIM: 609721; MGI: 2156538; GeneCards: PKD1L1
Gene location (Human)
Chr.	Chromosome 7 (human)
End	47,948,466 bp
RNA expression pattern
	Top expressed in
	testicle; ; apex of heart; ; gonad; ; left ventricle; ; left testis; ; muscle of thigh; ; epithelium of colon; ; right testis; ; gastrocnemius muscle; ; right auricle of heart;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; calcium channel activity;
Cellular component	integral component of membrane; plasma membrane; cell projection; cilium; calcium channel complex; membrane; ciliary membrane; non-motile cilium;
Biological process	ion transport; detection of nodal flow; detection of mechanical stimulus; calcium ion transmembrane transport; left/right axis specification; calcium ion transport; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	168507
	171395
	ENSG00000158683
	n/a
	Q8TDX9
	n/a
	NM_138295
	XM_036157131
	NP_612152
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Polycystin 1 like 1, transient receptor potential channel interacting is a protein that in humans is encoded by the PKD1L1 gene.

Function

This gene encodes a member of the polycystin protein family containing 11 transmembrane domains, a receptor for egg jelly (REJ) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. The encoded protein may play a role in the male reproductive system. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008].

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158683 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Polycystin 1 like 1, transient receptor potential channel interacting". Retrieved 2017-10-16.

PKD1L1

Function

References

Further reading