PLEKHF2

PLEKHF2
Identifiers
Aliases	PLEKHF2, EAPF, PHAFIN2, ZFYVE18, pleckstrin homology and FYVE domain containing 2
External IDs	OMIM: 615208; MGI: 1919051; GeneCards: PLEKHF2
Gene location (Human)
Chr.	Chromosome 8 (human)
End	95,156,685 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	11,007,927 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; skin of thigh; ; palpebral conjunctiva; ; bronchial epithelial cell; ; skin of hip; ; monocyte; ; sperm; ; bone marrow; ; corpus epididymis; ; olfactory zone of nasal mucosa;
	Top expressed in
	granulocyte; ; right kidney; ; neural layer of retina; ; yolk sac; ; spermatocyte; ; morula; ; proximal tubule; ; endocardial cushion; ; lip; ; atrioventricular valve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; metal ion binding; phosphatidylinositol binding;
Cellular component	endosome; early endosome membrane; transport vesicle; endoplasmic reticulum; membrane;
Biological process	protein transport;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	79666
	71801
	ENSG00000175895
	ENSMUSG00000049969
	Q9H8W4
	Q91WB4
	NM_024613
	NM_175175
	NP_078889
	NP_780384
	Wikidata
View/Edit Human	View/Edit Mouse

Pleckstrin homology domain-containing family F member 2 is a protein that in humans is encoded by the PLEKHF2 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000175895 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049969 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2".

Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 8 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000175895 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000049969 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2".

PLEKHF2

References

Further reading