PSD3

PSD3

Identifiers

PSD3, EFA6R, HCA67, EFA6D, pleckstrin and Sec7 domain containing 3

External IDs

OMIM: 614440; MGI: 1918215; GeneCards: PSD3

Gene location (Human)

Chr.	Chromosome 8 (human)

Band	8p22	Start	18,527,303 bp
Band	8p22	End	19,084,730 bp

Gene location (Mouse)

Chr.	Chromosome 8 (mouse)

Band	8\|8 B3.2-B3.3	Start	67,689,082 bp
Band	8\|8 B3.2-B3.3	End	68,212,027 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

Brodmann area 23

endothelial cell

cerebellar vermis

middle temporal gyrus

lateral nuclear group of thalamus

parietal lobe

postcentral gyrus

entorhinal cortex

Achilles tendon

superior frontal gyrus

Top expressed in

subiculum

Region I of hippocampus proper

cingulate gyrus

primary motor cortex

anterior amygdaloid area

lobe of cerebellum

prefrontal cortex

cerebellar vermis

medial dorsal nucleus

mammillary body

More reference expression data


More reference expression data

Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity
Cellular component	synapse membrane cell junction postsynaptic density postsynaptic membrane plasma membrane ruffle membrane cell projection
Biological process	regulation of ARF protein signal transduction
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


23362


234353


ENSG00000156011


ENSMUSG00000030465


Q9NYI0


Q2PFD7

RefSeq (mRNA)


NM_015310 NM_206909 NM_001362819


NM_027626 NM_030263 NM_177698

RefSeq (protein)


NP_056125 NP_996792 NP_001349748


NP_081902 NP_084539 NP_808366

Location (UCSC)

Chr 8: 18.53 – 19.08 Mb

Chr 8: 67.69 – 68.21 Mb

PubMed search

View/Edit Human

View/Edit Mouse

PH and SEC7 domain-containing protein 3 is a protein that in humans is encoded by the PSD3 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000156011 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000030465 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: PSD3 pleckstrin and Sec7 domain containing 3".

Further reading

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
Pils D, Horak P, Gleiss A, et al. (2006). "Five genes from chromosomal band 8p22 are significantly down-regulated in ovarian carcinoma: N33 and EFA6R have a potential impact on overall survival". Cancer. 104 (11): 2417–29. doi:10.1002/cncr.21538. PMID 16270321. S2CID 26030376.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Wang Y, Han KJ, Pang XW, et al. (2002). "Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies". J. Immunol. 169 (2): 1102–9. doi:10.4049/jimmunol.169.2.1102. PMID 12097419.
Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 6 (1): 63–70. doi:10.1093/dnares/6.1.63. PMID 10231032.

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