Paralytic peptides

Available protein structures:
PDB	IPR003463 PF02425 (ECOD; PDBsum)
AlphaFold	IPR003463; PF02425;

GBP_PSP
GBP_PSP
	Structure of a paralytic peptide from an insect, Manduca sexta
Identifiers
Symbol	GBP_PSP
Pfam	PF02425
InterPro	IPR003463
SCOP2	1b1v / SCOPe / SUPFAM
OPM superfamily	156
OPM protein	2eqt
PDB
Available protein structures:
PDB	IPR003463 PF02425 (ECOD; PDBsum)
AlphaFold	IPR003463; PF02425;

Paralytic peptides are a family of short (23 amino acids) insect peptides that halt metamorphosis of insects from larvae to pupae. These peptides contain one disulphide bridge. The family includes growth-blocking peptide (GBP) of Mythimna separata (Oriental armyworm) and the paralytic peptides from Manduca sexta (tobacco hawkmoth), Heliothis virescens (noctuid moth), and Spodoptera exigua (beet armyworm) as well as plasmatocyte-spreading peptide (PSP1).

References

↑ Skinner WS, Dennis PA, Li JP, Summerfelt RM, Carney RL, Quistad GB (July 1991). "Isolation and identification of paralytic peptides from hemolymph of the lepidopteran insects Manduca sexta, Spodoptera exigua, and Heliothis virescens". Journal of Biological Chemistry. 266 (20): 12873–7. doi:10.1016/S0021-9258(18)98775-2. PMID 2071576.
↑ Volkman BF, Anderson ME, Clark KD, Hayakawa Y, Strand MR, Markley JL (February 1999). "Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens". Journal of Biological Chemistry. 274 (8): 4493–6. doi:10.1074/jbc.274.8.4493. PMID 9988679.

This article incorporates text from the public domain Pfam and InterPro: IPR003463

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[pmid2071576-1] Skinner WS, Dennis PA, Li JP, Summerfelt RM, Carney RL, Quistad GB (July 1991). "Isolation and identification of paralytic peptides from hemolymph of the lepidopteran insects Manduca sexta, Spodoptera exigua, and Heliothis virescens". Journal of Biological Chemistry. 266 (20): 12873–7. doi:10.1016/S0021-9258(18)98775-2. PMID 2071576.

[pmid9988679-2] Volkman BF, Anderson ME, Clark KD, Hayakawa Y, Strand MR, Markley JL (February 1999). "Structure of the insect cytokine peptide plasmatocyte-spreading peptide 1 from Pseudoplusia includens". Journal of Biological Chemistry. 274 (8): 4493–6. doi:10.1074/jbc.274.8.4493. PMID 9988679.