Phaseolin (protein)

Phaseolin is the main reserve globulin in seeds of the French bean (Phaseolus vulgaris L.). It was named and first isolated and characterized by Thomas Burr Osborne in 1894.

Phaseolin is able to inhibit the activity of the enzyme α-amylase, which is responsible for the cleavage of carbohydrates. Phaseolin-containing plant extracts are used because of this nutritional property in food supplements and medical products. Phaseolin is the subject of various patent applications.

References

↑ Zheng Z, Sumi K, Tanaka K, Murai N (November 1995). "The Bean Seed Storage Protein [beta]-Phaseolin Is Synthesized, Processed, and Accumulated in the Vacuolar Type-II Protein Bodies of Transgenic Rice Endosperm". Plant Physiology. 109 (3): 777–786. doi:10.1104/pp.109.3.777. JSTOR 4276867. PMC 161377. PMID 12228632.
↑ Blagrove RJ, Colman PM, Lilley GG, Van Donkelaar A, Suzuki E (1983). "Physicochemical and structural studies of phaseolin from French bean seed". Plant Foods for Human Nutrition. 33 (2–3): 227–9. doi:10.1007/BF01091313.
↑ Osborne TB (1894). "The Proteids of the Kidney Bean". Journal of the American Chemical Society. 16 (10): 703–12. doi:10.1021/ja02108a012.
↑ Yao Y, Hu Y, Zhu Y, Gao Y, Ren G (2016). "Comparisons of phaseolin type and α-amylase inhibitor in common bean (Phaseolus vulgaris L.) in China". The Crop Journal. 4: 68–72. doi:10.1016/j.cj.2015.09.002.
↑ DE application DE202014003391U1, Schmitt P, "Nahrungsergänzungsmittel zur Unterstützung einer kalorienreduzierten Ernährung [Dietary supplement to support a calorie restricted diet]"
↑ DE application DE202015002279U1, Schmitt P, "Nahrungsergänzungsmittel zur Aufrechterhaltung eines normalen Blutzuckerspiegels [Dietary supplement to maintain a normal blood sugar level]"

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[1] Zheng Z, Sumi K, Tanaka K, Murai N (November 1995). "The Bean Seed Storage Protein [beta]-Phaseolin Is Synthesized, Processed, and Accumulated in the Vacuolar Type-II Protein Bodies of Transgenic Rice Endosperm". Plant Physiology. 109 (3): 777–786. doi:10.1104/pp.109.3.777. JSTOR 4276867. PMC 161377. PMID 12228632.

[2] Blagrove RJ, Colman PM, Lilley GG, Van Donkelaar A, Suzuki E (1983). "Physicochemical and structural studies of phaseolin from French bean seed". Plant Foods for Human Nutrition. 33 (2–3): 227–9. doi:10.1007/BF01091313.

[3] Osborne TB (1894). "The Proteids of the Kidney Bean". Journal of the American Chemical Society. 16 (10): 703–12. doi:10.1021/ja02108a012.

[4] Yao Y, Hu Y, Zhu Y, Gao Y, Ren G (2016). "Comparisons of phaseolin type and α-amylase inhibitor in common bean (Phaseolus vulgaris L.) in China". The Crop Journal. 4: 68–72. doi:10.1016/j.cj.2015.09.002.

[5] DE application DE202014003391U1, Schmitt P, "Nahrungsergänzungsmittel zur Unterstützung einer kalorienreduzierten Ernährung [Dietary supplement to support a calorie restricted diet]"

[6] DE application DE202015002279U1, Schmitt P, "Nahrungsergänzungsmittel zur Aufrechterhaltung eines normalen Blutzuckerspiegels [Dietary supplement to maintain a normal blood sugar level]"