Phellibaumin

Phellibaumins are hispidin derivatives isolated from the fungus Phellinus. Five such derivatives have been identified, designated as phellibaumins A through E. Phellibaumins A and B are classified as pyranones, while phellibaumins C, D, and E are classified as styrylpyranones.

Phellibaumin A was also identified as being produced by the fungus Inonotus hispidus, and phellibaumins B and C were identified in Sanghuangporus vaninii. Phellibaumin E is of interest to medical researchers due to potential anti-dementia effects.

Chemical structures

References

  1. ↑ Wu, Chang-Sheng; Lin, Zhao-Min; Wang, Li-Ning; Guo, Dong-Xiao; Wang, Shu-Qi; Liu, Yong-Qing; Yuan, Hui-Qing; Lou, Hong-Xiang (2011-06-01). "Phenolic compounds with NF-κB inhibitory effects from the fungus Phellinus baumii". Bioorganic & Medicinal Chemistry Letters. 21 (11): 3261–3267. doi:10.1016/j.bmcl.2011.04.025. ISSN 1464-3405. PMID 21531558.
  2. ↑ "Chemical constituents from Phellinus igniarius and their anti-tumor activity in vitro". China Journal of Chinese Materia Medica. 2016-08-15. doi:10.4268/cjcmm20161617 (inactive 18 July 2025).{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)
  3. ↑ Cao, Yinglong; Liu, Yi; Wang, Ge; Wang, Wenqiong; Li, Yougui; Xuan, Lijiang (2021-08-01). "Styryl pyranones with apoptosis activities from the sporocarps of Phellinus igniarius". Phytochemistry Letters. 44: 154–159. Bibcode:2021PChL...44..154C. doi:10.1016/j.phytol.2021.06.018. ISSN 1874-3900.
  4. ↑ He, Pingya; Zhang, Yi; Li, Ning (2021). "The phytochemistry and pharmacology of medicinal fungi of the genus Phellinus : a review". Food & Function. 12 (5): 1856–1881. doi:10.1039/D0FO02342F. ISSN 2042-6496. PMID 33576366.
  5. ↑ Li, Qingjie; Bao, Haiying; Bau, Tolgor; Li, Yu (2018). "Influence of Inonotus hispidus in hemorheology in rat model with blood stasis due to cold syndrome and analysis on spectral efficiency". Journal of Jilin University (Medicine Edition) (in Chinese): 30–35. doi:10.13481/j.1671-587x.20180106.
  6. ↑ Zhang, Yangyang; Lv, Guoying; Song, Tingting; Chen, Chun; Zhang, Zuofa; Cai, Weiming (2022-09-06). "Recovery of the phenolic compounds from artificial cultivated Sanghuangporus vaninii using a green method and biological properties of phenolic extract in vitro". International Journal of Food Science & Technology. 58 (7): 3969–3981. doi:10.1111/ijfs.15993. ISSN 0950-5423.
  7. ↑ Liu, Ruoyao; Zhang, Yuchi; Li, Sainan; Liu, Chunming; Zhuang, Siyuan; Zhou, Xu; Li, Yanjie; Liang, Jiaqi (2022-10-15). "Receptor-ligand affinity-based screening and isolation of water-soluble 5-lipoxygenase inhibitors from Phellinus igniarius". Journal of Chromatography B. 1209 123415. doi:10.1016/j.jchromb.2022.123415. ISSN 1570-0232. PMID 35973282.