Philip Seeman

Philip Seeman
Born(1934-02-08)8 February 1934
Winnipeg, Manitoba, Canada
Died9 January 2021(2021-01-09) (aged 86)
Toronto, Ontario, Canada
EducationBachelor of Science
Master of Science degree
Ph.D. in life sciences
Alma materMcGill University
Rockefeller University
OccupationPharmacologist
AwardsOrder of Canada

Philip Seeman, OC FRSC (8 February 1934 – 9 January 2021) was a Canadian schizophrenia researcher and neuropharmacologist, known for his research on dopamine receptors.

Career

Born in Winnipeg, Manitoba, Seeman was raised in Montreal. He received a Bachelor of Science degree, honours physics & physiology (1955), a Master of Science degree, physiology of transport & secretion (1956), and a Doctor of Medicine (1960) from McGill University. In 1966, he received a Ph.D. in life sciences from Rockefeller University under the supervision of George Emil Palade.

In 1967, Seeman became an assistant professor in the Department of Pharmacology at the University of Toronto. In 1970, he was appointed a professor.

In 1974, having spent years in search of the binding site of antipsychotic medication, he discovered the dopamine D2 receptor, the basis for the dopamine hypothesis of schizophrenia. His discoveries also helped advance research on other diseases involving dopamine, such as Parkinson's disease and Huntington's disease.

In 1985, he was made a Fellow of the Royal Society of Canada.

In 2001, he was made an Officer of the Order of Canada "for his research on dopamine receptors and their involvement in diseases such as schizophrenia, Parkinson's and Huntington's".

He was married to Dr. Mary V. Seeman.

Notes

  1. ↑ "Philip SEEMAN". The Globe and Mail. Retrieved 19 January 2021.
  2. 1 2 Peters, Diane (27 January 2021). "Researcher Philip Seeman shed new light on biology of schizophrenia". The Globe and Mail. Retrieved 15 August 2024.
  3. ↑ P. Seeman, M. Chau-Wong, J. Tedesco & K. Wong (November 1975). "Brain receptors for antipsychotic drugs and dopamine: direct binding assays". Proceedings of the National Academy of Sciences of the United States of America. 72 (11): 4376–4370. Bibcode:1975PNAS...72.4376S. doi:10.1073/pnas.72.11.4376. PMC 388724. PMID 1060115.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ↑ "People". CMAJ. 151 (8): 1186–1187. 1994. PMC 1337253.
  5. ↑ "Science & Medicine - Science & Medicine". www.sciandmed.com. Archived from the original on 2011-07-16.
  6. ↑ Order of Canada citation (archived)
  7. ↑ "Most Wikipedia profiles are about men – these women in Australia are hoping to change that". SBS News. Retrieved 27 July 2019.

References