Phosphomolybdic acid

Phosphomolybdic acid
Names
Other names
Molybdophosphoric acid; dodecamolybdophosphoric acid
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.031.544 Edit this at Wikidata
EC Number
  • 234-713-5
MeSH Phosphomolybdic+acid
UNII
  • InChI=1S/12Mo.H3O4P.36O/c;;;;;;;;;;;;1-5(2,3)4;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h;;;;;;;;;;;;(H3,1,2,3,4);;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;
    Key: DHRLEVQXOMLTIM-UHFFFAOYSA-N
  • OP(=O)(O)O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O.O=[Mo](=O)=O
  • [Mo]18%21%24(O[Mo]%16%18%23(O[Mo]56(O1)(O[Mo]247(O[Mo]9%22(O[Mo]%12%13(O2)(O[Mo]3%11%14(O[Mo]%17%19(O[Mo](O3)(O4)(O5)([O++]67[P+]%15%20[O++]89[Mo]%10(O[Mo](O[Mo](O%10)(O%11)(O%12)([O++]%13%14%15)[O-])(O%16)(O%17)([O++]%18%19%20)[O-])(O%21)(O%22)[O-])[O-])(O%23)[O-])[O-])O)(O%24)[O-])[O-])O)[O-])O
Properties
H3[PMo12O40]
Molar mass 1825.25 g/mol
Density 1.62 g/ml (hydrate)
Melting point 79-90 °C
soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Oxidiser (hydrate)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phosphomolybdic acid is the heteropolymetalate with the formula H3[Mo12PO40]·12H2O. It is a yellow solid, although even slightly impure samples have a greenish coloration. It is also known as dodeca molybdophosphoric acid or PMA, is a yellow-green chemical compound that is freely soluble in water and polar organic solvents such as ethanol. It is used as a stain in histology and in organic synthesis.

Histology

Phosphomolybdic acid is a component of Masson's trichrome stain.

Organic synthesis

Phosphomolybdic is used as a stain for developing thin-layer chromatography plates, staining phenolics, hydrocarbon waxes, alkaloids, and steroids. Conjugated unsaturated compounds reduce PMA to molybdenum blue. The color intensifies with increasing number of double bonds in the molecule being stained.

Phosphomolybdic acid is also occasionally used in acid-catalyzed reactions in organic synthesis. It has been shown to be a good catalyst for the Skraup reaction for the synthesis of substituted quinolines.

Bismuth phosphomolybdate catalyzes ammoxidation in the Sohio process.

See also

References

  1. 1 2 3 "Phosphomolybdic acid hydrate - Safety data sheet" (PDF). www.sigmaaldrich.com. 2016-07-18. Retrieved 2018-10-06.
  2. ↑ Dias, J. A.; Dias, S. C. L.; Caliman, E. (2014). "Keggin Structure Polyoxometalates". Inorganic Syntheses: Volume 36. Inorganic Syntheses. Vol. 36. p. 210-217. doi:10.1002/9781118744994.ch39. ISBN 9781118744994.
  3. ↑ "Masson's Trichrome for Muscle and Collagen". StainsFile. Archived from the original on 2013-07-02. Retrieved 2018-10-06.
  4. ↑ "Stains for Developing TLC Plates" (PDF). McMaster University.
  5. ↑ Burstein, Shlomo (1953). "Reduction of Phosphomolybdic Acid by Compounds Possessing Conjugated Double Bonds". Analytical Chemistry. 25 (3): 422–424. doi:10.1021/ac60075a012. ISSN 0003-2700 – via ACS Publications.
  6. ↑ Chaskar, Atul; Padalkar, Vikas; Phatangare, Kiran; et al. (2010). "Miceller-Mediated Phosphomolybdic Acid: Highly Effective Reusable Catalyst for Synthesis of Quinoline and Its Derivatives". Synthetic Communications. 40 (15): 2336–2340. doi:10.1080/00397910903245141. ISSN 0039-7911. S2CID 94978408 – via Taylor & Francis Online.
  7. ↑ "Sohio Acrylonitrile process". ACS Chemical Landmarks. Washington, DC: American Chemical Society. 2007. Retrieved 1 Aug 2024.