Pipecuronium bromide

Pipecuronium bromide
Clinical data
Trade namesArduan
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • (2β,3α,5α,16β,17β)-3,17-bis(acetyloxy)-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)androstane dibromide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.052.475 Edit this at Wikidata
Chemical and physical data
FormulaC35H62Br2N4O4
Molar mass762.713 g·mol−1
3D model (JSmol)
  • [Br-].[Br-].O=C(O[C@H]6[C@@H](N1CC[N+](C)(C)CC1)C[C@@H]5[C@]6(C)CC[C@H]3[C@H]5CC[C@H]4C[C@H](OC(=O)C)[C@@H](N2CC[N+](CC2)(C)C)C[C@]34C)C
  • InChI=1S/C35H62N4O4.2BrH/c1-24(40)42-32-21-26-9-10-27-28(35(26,4)23-31(32)37-15-19-39(7,8)20-16-37)11-12-34(3)29(27)22-30(33(34)43-25(2)41)36-13-17-38(5,6)18-14-36;;/h26-33H,9-23H2,1-8H3;2*1H/q+2;;/p-2/t26-,27+,28-,29-,30-,31-,32-,33-,34-,35-;;/m0../s1 checkY
  • Key:TXWBOBJCRVVBJF-YTGGZNJNSA-L checkY
 X markNcheckY (what is this?)  (verify)

Pipecuronium (Arduan) is a bisquaternary aminosteroid muscle relaxant which blocks nicotinic acetylcholine receptors at the neuromuscular junction. It is also an antagonist of M2 and M3 muscarinic receptors and is the most potent neuromuscular blocking agent of the aminosteroid class.[citation needed]

It is sold under the trade names Arduan and Pycuron.

See also

References

  1. ↑ "Pipecuronium Bromide". WHOCC - ATC/DDD Index. M03AC06.
  2. 1 2 "Pipecuronium". DrugBank.
  3. ↑ Singh H, Jindal DP, Yadav MR, Kumar M (January 1991). "5 Heterosteroids and drug research.". Progress in Medicinal Chemistry. Vol. 28. pp. 233-300 (270). doi:10.1016/S0079-6468(08)70366-7. ISBN 978-0-444-81275-9. PMID 1843548.
  4. ↑ "Pipecuronium - brand name list from". Drugs.com. Retrieved 2022-09-17.