Plasma needling

Plasma needling is a minimally invasive aesthetic medical procedure purported to rejuvenate skin, minimize the appearance of hypertrophic and hypotrophic scars and stretchmarks, and reduce pattern hair loss through multimodal physical and biochemical cellular stimulation. It is a combination of classical medical micro-needling by Dermaroller or DermaPen. Both are used in Collagen induction therapy and PRP (platelet-rich plasma). The latter is used in Prolotherapy as well as in the Vampire facelift. The effects on fibroblasts, cells, and micro-needling stem cells are published in scientific publications regarding micro-needling, and the injection of PRP, has also been tested as a combined treatment.

References

↑ Fabbrocini, G; De Vita, V; Pastore, F; Annunziata, MC; Cacciapuoti, S; Monfrecola, A; Cameli, N; Tosti, A (Apr 2012). "Collagen induction therapy for the treatment of upper lip wrinkles". J. Dermatolog. Treat. 23 (2): 144–52. doi:10.3109/09546634.2010.544709. PMID 21810012. S2CID 34680894.
↑ Majid, Imran (2009). "Microneedling therapy in atrophic facial scars: An objective assessment". J. Cutan. Aesthet. Surg. 2 (1): 26–30. doi:10.4103/0974-2077.53096. PMC 2840919. PMID 20300368.
↑ Liebl, Horst; Kloth, Luther C.; PT; MS; Fapta, CWS; Faccws (2012). "Skin Cell Proliferation Stimulated by Microneedles". J. Am. Coll. Clin. Wound Spec. 4 (1): 2–6. doi:10.1016/j.jccw.2012.11.001. PMC 3921236. PMID 24527373.
↑ Ramos-Torrecillas, J; Luna-Bertos Ed, Manzano-Moreno FJ; García-Martínez, O; Ruiz, C (Mar 2014). "Human fibroblast-like cultures in the presence of platelet-rich plasma as a single growth factor source: clinical implications". Adv. Skin Wound Care. 27 (3): 114–20. doi:10.1097/01.ASW.0000443266.17665.19. hdl:10481/93829. PMID 24531517. S2CID 205385849.
↑ Yuksel, EP; Sahin, G; Aydin, F; Senturk, N; Turanli, AY (Oct 2014). "Evaluation of effects of platelet-rich plasma on human facial skin". J. Cosmet. Laser Ther. 16 (5): 206–8. doi:10.3109/14764172.2014.949274. PMID 25065381. S2CID 5908351.
↑ Cervelli, V; Garcovich, S; Bielli, A; Cervelli, G; Curcio, BC; Scioli, MG; Orlandi, A; Gentile, P (2014). "The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation". Biomed Res. Int. 2014 760709. doi:10.1155/2014/760709. PMC 4032742. PMID 24883322.
↑ Fabi, S; Sundaram, H (Apr 2014). "The potential of topical and injectable growth factors and cytokines for skin rejuvenation". Facial Plast. Surg. 30 (2): 157–71. doi:10.1055/s-0034-1372423. PMID 24810127.
↑ Nofal, E; Helmy, A; Nofal, A; Alakad, R; Nasr, M (Aug 2014). "Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study". Dermatol. Surg. 40 (8): 864–73. doi:10.1111/dsu.0000000000000091 (inactive 12 July 2025). PMID 25006854.{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)

[1] Fabbrocini, G; De Vita, V; Pastore, F; Annunziata, MC; Cacciapuoti, S; Monfrecola, A; Cameli, N; Tosti, A (Apr 2012). "Collagen induction therapy for the treatment of upper lip wrinkles". J. Dermatolog. Treat. 23 (2): 144–52. doi:10.3109/09546634.2010.544709. PMID 21810012. S2CID 34680894.

[2] Majid, Imran (2009). "Microneedling therapy in atrophic facial scars: An objective assessment". J. Cutan. Aesthet. Surg. 2 (1): 26–30. doi:10.4103/0974-2077.53096. PMC 2840919. PMID 20300368.

[3] Liebl, Horst; Kloth, Luther C.; PT; MS; Fapta, CWS; Faccws (2012). "Skin Cell Proliferation Stimulated by Microneedles". J. Am. Coll. Clin. Wound Spec. 4 (1): 2–6. doi:10.1016/j.jccw.2012.11.001. PMC 3921236. PMID 24527373.

[4] Ramos-Torrecillas, J; Luna-Bertos Ed, Manzano-Moreno FJ; García-Martínez, O; Ruiz, C (Mar 2014). "Human fibroblast-like cultures in the presence of platelet-rich plasma as a single growth factor source: clinical implications". Adv. Skin Wound Care. 27 (3): 114–20. doi:10.1097/01.ASW.0000443266.17665.19. hdl:10481/93829. PMID 24531517. S2CID 205385849.

[5] Yuksel, EP; Sahin, G; Aydin, F; Senturk, N; Turanli, AY (Oct 2014). "Evaluation of effects of platelet-rich plasma on human facial skin". J. Cosmet. Laser Ther. 16 (5): 206–8. doi:10.3109/14764172.2014.949274. PMID 25065381. S2CID 5908351.

[6] Cervelli, V; Garcovich, S; Bielli, A; Cervelli, G; Curcio, BC; Scioli, MG; Orlandi, A; Gentile, P (2014). "The effect of autologous activated platelet rich plasma (AA-PRP) injection on pattern hair loss: clinical and histomorphometric evaluation". Biomed Res. Int. 2014 760709. doi:10.1155/2014/760709. PMC 4032742. PMID 24883322.

[7] Fabi, S; Sundaram, H (Apr 2014). "The potential of topical and injectable growth factors and cytokines for skin rejuvenation". Facial Plast. Surg. 30 (2): 157–71. doi:10.1055/s-0034-1372423. PMID 24810127.

[8] Nofal, E; Helmy, A; Nofal, A; Alakad, R; Nasr, M (Aug 2014). "Platelet-rich plasma versus CROSS technique with 100% trichloroacetic acid versus combined skin needling and platelet rich plasma in the treatment of atrophic acne scars: a comparative study". Dermatol. Surg. 40 (8): 864–73. doi:10.1111/dsu.0000000000000091 (inactive 12 July 2025). PMID 25006854.{{cite journal}}: CS1 maint: DOI inactive as of July 2025 (link)