In the United States, a practice agreement is a written document between a physician and one or more other licensed health professionals that sets out the medical duties the professionals can perform, the conditions attached to that work, and the oversight the physician provides. State law gives the instrument many different names. Among them are collaborative practice agreement, supervision agreement, delegation agreement, standard care arrangement, prescriptive authority agreement and written protocol. The name a jurisdiction chooses usually signals the legal theory on which the professional's authority rests.
Practice agreements are creatures of state law. A state's medical practice act, together with the acts governing nursing, physician assistants and pharmacy, determines whether an agreement is required, who signs it, what it must contain, whether it is filed with or approved by a licensing board, and how many clinicians one physician may cover. Nurse practitioners and other advanced practice registered nurses, physician assistants, pharmacists and, for specific delegated tasks, registered nurses practice under them. There is no federal practice agreement; federal payment programs such as Medicare generally defer to state scope-of-practice law in determining whether a service was lawfully furnished.
The requirement has been a central subject of the scope of practice debate in American health policy. Between 2010 and 2026 a majority of states removed or reduced the agreement requirement for nurse practitioners while extending agreement-based authority to pharmacists. As a result, the number of professions practicing under such an instrument grew even as the number of states requiring one for any given profession fell.
No single term is used nationally. A 2026 survey of the 50 states, the District of Columbia and Puerto Rico identified 57 distinct statutory or regulatory names for the instrument across the three principal professions. The names fall into four broad families. The family a state's term belongs to is generally a better guide to the substance of the requirement than the term itself:
Several states use a term from one family for a mechanism that belongs to another. Florida calls the nurse practitioner instrument a written protocol, although the underlying relationship is supervisory, and Mississippi recognizes a "board-approved protocol or standing order" for nurse practitioners. Terms are also reused across professions with different meanings: written protocol names the pharmacist instrument in Texas, Alaska, Mississippi and New Jersey, and the nurse practitioner and physician assistant instrument in Florida.
A related but distinct instrument, the medical director agreement, names a physician as the clinical authority for a facility or business, such as a medical spa, an urgent care clinic, an opioid treatment program or a home-care company, rather than for an individual clinician. All 52 jurisdictions surveyed recognize some form of it, and a practice may need both.
Practice agreements arise from three separate bodies of state law that do not always align.
The medical practice act defines the practice of medicine and the circumstances in which a physician may delegate parts of it. Delegation-family instruments derive directly from this authority; Michigan, for example, permits a licensee to delegate acts to a person otherwise unlicensed to perform them, subject to supervision.
The professional practice act for the second profession sets the conditions on that profession's own license. New York requires a nurse practitioner to have a written practice agreement with a collaborating physician for the first 3,600 hours of practice, and Virginia provides for a practice agreement covering both nurse practitioners and physician assistants.
Board rules supply most of the operative detail. The required contents of an agreement, the frequency of chart review, the retention period and any filing obligation are usually found in regulations of the board of medicine, board of nursing or board of pharmacy rather than in statute. North Carolina's requirements for nurse practitioners appear in the joint rules of its medical and nursing boards, and Massachusetts sets its collaborative drug therapy management requirements by regulation.
These three bodies of law can disagree, as when a nursing board rule permits what a medical board rule restricts, or the reverse. Practices in the affected state generally follow the more restrictive requirement, because either board may discipline its own licensee.
Required contents vary by state, but the elements recur across jurisdictions:
Texas requires a prescriptive authority agreement to state the parties' names, addresses and license numbers; the nature of each party's practice and its locations; the categories of drugs covered; and a plan for consultation, referral and emergency coverage. The agreement must be reviewed annually.
Filing practice differs sharply. Some states require the agreement only to be held at the practice site and produced on request; others require registration with a board before the professional may practice. Most states do not require the physician to be present on site, and agreements are commonly held with a physician at a different location. Critics and defenders of that arrangement, sometimes called remote collaboration, characterize it very differently.
The requirement for nurse practitioners has changed more than for any other profession. The National Council of State Boards of Nursing's 2008 APRN Consensus Model recommended that advanced practice registered nurses be licensed as independent practitioners without a required written agreement with a physician, and the Institute of Medicine's 2011 report The Future of Nursing recommended that nurses be permitted to practice to the full extent of their education and training.
The American Association of Nurse Practitioners classifies state practice environments as full, reduced or restricted, the last two turning on whether a career-long regulated agreement with a physician is required. Some states require an agreement only for a transitional period: Nebraska uses a transition-to-practice arrangement, and New York's agreement requirement lapses after 3,600 hours.
Physician assistants practice under an agreement in most states, and the supervision family of terms predominates. Several states have moved from supervision to collaboration language. Maryland and Oregon use collaboration agreement. Others have replaced the individual agreement with a practice-level obligation: West Virginia uses a practice notification. Minnesota eliminated its physician-agreement requirement for experienced physician assistants, retaining a written practice agreement with the employing practice. Missouri uses a single collaborative practice arrangement covering both nurse practitioners and physician assistants. Florida sets the physician assistant requirement in its Medical Practice Act.
For pharmacists the instrument authorizes collaborative drug therapy management (CDTM): initiating, modifying or discontinuing drug therapy, and ordering related laboratory tests, under a written agreement with a prescriber. Every jurisdiction surveyed except two now recognizes some form of it. California authorizes pharmacists to perform specified functions under protocol, Washington and Maine provide for collaborative drug therapy agreements by regulation and by statute, respectively, and the Centers for Disease Control and Prevention has published implementation guidance promoting the agreements as a means of adding pharmacists to care teams for chronic disease management.
Pharmacist agreements differ from the nursing and physician assistant instruments in that they are typically population- or condition-specific rather than general, and are often held with an institution rather than a named physician.
A smaller number of states extend the mechanism further. Georgia uses a nurse protocol agreement permitting a registered nurse to order drugs and devices under physician protocol, and several states authorize registered nurses to administer specified treatments under a standing order or protocol without an individual agreement.
The table lists the principal instrument each jurisdiction names for the three professions most often covered. A dash indicates that the jurisdiction does not name a specific instrument for that profession; where a jurisdiction names more than one, both appear. Names are those used in the governing statute or board rule as of September 2026.
| Jurisdiction | Nurse practitioner | Physician assistant | Pharmacist |
|---|---|---|---|
| Alabama | Standard Protocol | Supervisory Practice Agreement | CDTM Agreement |
| Alaska | - | Collaborative Plan | Written Protocol |
| Arizona | - | Written Supervision Agreement | Collaborative Practice Agreement |
| Arkansas | Collaborative Practice Agreement | Delegation Agreement | Collaborative Practice Agreement |
| California | Standardized Procedures | Practice Agreement | Collaborative Practice Agreement |
| Colorado | Articulated Plan | Supervisory Practice Agreement / Collaborative Agreement | Collaborative Pharmacy Practice Agreement |
| Connecticut | Supervisory Practice Agreement | Written Delegation Agreement | Collaborative Drug Therapy Management Agreement or Care Plan |
| Delaware | Collaborative Agreement | Supervisory Practice Agreement | Collaborative Pharmacy Practice Agreement |
| District of Columbia | - | Delegation Agreement | Collaborative Practice Agreement |
| Florida | Written Protocol | Written Protocol | Written Collaborative Pharmacy Practice Agreement |
| Georgia | Nurse Protocol Agreement | Job Description | Drug Therapy Modification Protocol |
| Hawaii | - | Supervisory Practice Agreement | Written Collaborative Agreement |
| Idaho | - | Supervisory Practice Agreement | Written Collaborative Pharmacy Practice Agreement |
| Illinois | Written Collaborative Agreement | Written Collaborative Agreement | - |
| Indiana | Written Collaborative Practice Agreement | Written Supervisory Agreement | Written Collaborative Practice Protocol |
| Iowa | - | Supervisory Practice Agreement | Written Collaborative Pharmacy Practice Agreement |
| Kansas | - | Supervisory Practice Agreement | Written Collaborative Practice Agreement |
| Kentucky | Collaborative Agreement for Prescriptive Authority | Supervisory Practice Agreement | Written Collaborative Care Agreement |
| Louisiana | Collaborative Practice Agreement | Supervisory Practice Agreement | Collaborative Drug Therapy Management Order Set |
| Maine | Supervisory Practice Agreement | Collaborative Agreement | CDTM Agreement |
| Maryland | - | Collaboration Agreement | Prescriber-pharmacist Agreement |
| Massachusetts | Written Collaborative Arrangement | Supervisory Practice Agreement | Collaborative Practice Agreement |
| Michigan | Delegation Agreement | Written Practice Agreement | Delegation Agreement |
| Minnesota | Collaborative Agreement | Written Practice Agreement | Written Collaborative Practice Agreement |
| Mississippi | Board-approved Protocol or Standing Order | Written Practice Protocol | Written Protocol |
| Missouri | Collaborative Practice Arrangement | Collaborative Practice Arrangement | - |
| Montana | - | Supervisory Practice Agreement | Written Collaborative Pharmacy Practice Agreement |
| Nebraska | Transition-to-practice Arrangement | Written Collaborative Agreement | Written Practice Agreement |
| Nevada | - | Written Supervisory Agreement | Collaborative Practice Agreement |
| New Hampshire | - | Written Collaboration Agreement | Collaborative Pharmacy Practice Agreement |
| New Jersey | Written Joint Protocol | Written Supervision Agreement | Written Protocol |
| New Mexico | - | Supervisory Practice Agreement | Written Guidelines or Protocol |
| New York | Written Practice Agreement | Supervisory Practice Agreement | Collaborative Drug Therapy Management Framework |
| North Carolina | Collaborative Practice Arrangement | Supervisory Practice Agreement | Written Collaborative Practice Agreement |
| North Dakota | - | - | Collaborative Practice Agreement |
| Ohio | Standard Care Arrangement | Supervision Agreement | Consult Agreement |
| Oklahoma | Supervision, Collaboration, and Referral Plan | Written Practice Agreement | Written Collaborative Practice Agreement |
| Oregon | - | Collaboration Agreement | CDTM Protocol |
| Pennsylvania | Collaborative Agreement / Prescriptive Authority Collaborative Agreement | Written Agreement | Collaborative Agreement |
| Puerto Rico | Written Collaborative Agreement | Supervisory Practice Agreement | Protocol |
| Rhode Island | - | Supervisory Practice Agreement | Written Collaborative Practice Agreement |
| South Carolina | Written Practice Agreement | Scope of Practice Guidelines | Collaborative Practice Agreement |
| South Dakota | Written Collaborative Agreement | Written Practice Agreement | Protocol |
| Tennessee | Collaborative Practice Agreement | Supervisory Practice Agreement | Collaborative Pharmacy Practice Agreement |
| Texas | Prescriptive Authority Agreement | Prescriptive Authority Agreement / Supervisory Practice Agreement | Written Protocol |
| Utah | - | Delegation of Services Agreement | Collaborative Pharmacy Practice Agreement |
| Vermont | Formal Collaborative Provider Agreement | Written Practice Agreement | Written Collaborative Practice Agreement |
| Virginia | Practice Agreement | Practice Agreement | Written Collaborative Agreement |
| Washington | - | Supervisory Practice Agreement / Collaboration Relationship | Collaborative Drug Therapy Agreement |
| West Virginia | Written Collaborative Agreement | Practice Notification | Collaborative Pharmacy Practice Notification |
| Wisconsin | Collaborative Arrangement | Written Collaborative Agreement | Delegation Agreement |
| Wyoming | - | Supervisory Practice Agreement | Collaborative Practice Agreement |
Many states cap the number of clinicians one physician may cover. Texas limits a delegating physician to seven full-time-equivalent advanced practice registered nurses and physician assistants combined, with exceptions for medically underserved areas and facility-based practice. Other states set the limit by headcount rather than full-time equivalents, count nurse practitioners and physician assistants separately, or set no numeric limit at all.
Further conditions commonly attached to an agreement include a geographic limit on the distance between the physician and the practice site; a requirement that the physician practice in a related specialty; a minimum frequency of on-site visits; a percentage of charts subject to review; and a minimum number of hours of experience before the professional may hold an agreement or practice without one.
Because the physician's participation is a condition of the second professional's licensure, the agreement usually carries a fee. A market has developed in which physicians contract to serve as the collaborating, supervising or delegating physician for practices in which they do not otherwise work. Critics describe these arrangements as a payment for a signature that produces no clinical oversight; defenders describe them as the mechanism that allows clinics in areas without a resident physician to operate at all.
The requirement is contested, and the arguments are largely economic and evidentiary rather than technical.
The Federal Trade Commission has argued that mandatory physician-supervision requirements can raise costs and restrict competition without a corresponding safety benefit, and has urged states to scrutinize them. The Institute of Medicine reached a similar conclusion on access grounds, and nursing organizations argue that the requirement bears no relation to the individual professional's competence and is a barrier to practice in rural and underserved areas.
The American Medical Association and other physician organizations oppose removing the requirement, arguing that differences in the length and content of training justify physician-led teams and that patients may not distinguish between clinician types.
A separate line of criticism accepts the requirement in principle but questions its administration: agreements that are signed and filed but never acted on, chart-review obligations that are not met, and physicians who cover the statutory maximum number of clinicians across several states. This critique is made by participants on both sides of the scope-of-practice question, since an unenforced requirement supplies neither the oversight its defenders claim nor the access its opponents seek.