RABEPK

RABEPK
Identifiers
Aliases	RABEPK, RAB9P40, bA65N13.1, p40, Rab9 effector protein with kelch motifs
External IDs	OMIM: 605962; MGI: 2139530; GeneCards: RABEPK
Gene location (Human)
Chr.	Chromosome 9 (human)
End	125,234,161 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	34,689,924 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; buccal mucosa cell; ; nucleus accumbens; ; putamen; ; caudate nucleus; ; prefrontal cortex; ; stromal cell of endometrium; ; right frontal lobe; ; Brodmann area 9; ; cingulate gyrus;
	Top expressed in
	spermatid; ; seminiferous tubule; ; spermatocyte; ; yolk sac; ; dentate gyrus of hippocampal formation granule cell; ; embryo; ; epiblast; ; embryo; ; blastocyst; ; right kidney;
	More reference expression data
	More reference expression data
Orthologs
Databases	NCBI: entry; OMA: entry
	10244
	227746
	ENSG00000136933
	ENSMUSG00000070953
	Q7Z6M1; Q5T1S5
	Q8VCH5
	NM_001174152; NM_001174153; NM_005833
	NM_145522; NM_001374669
	NP_001167623; NP_001167624; NP_005824
	NP_663497; NP_001361598
	Wikidata
View/Edit Human	View/Edit Mouse

Rab9 effector protein with Kelch motifs also known as p40 is a protein that in humans is encoded by the RABEPK gene.

Membrane-associated p40, in together with RAB9A, facilitates the transport of the mannose 6-phosphate receptor (MPR) from endosomes to the trans-Golgi network.

Interactions

RABEPK has been shown to interact with RAB9A and FYVE finger-containing phosphoinositide kinase.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000136933 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070953 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 3 Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol. 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197. PMID 9230071.
↑ "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs".
↑ Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284.

External links

RABEPK human gene location in the UCSC Genome Browser.
RABEPK human gene details in the UCSC Genome Browser.

This article on a gene on human chromosome 9 is a stub. You can help Wikipedia by adding missing information.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000136933 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000070953 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9230071-5] 1 2 3 Diaz E, Schimmoller F, Pfeffer SR (Aug 1997). "A novel Rab9 effector required for endosome-to-TGN transport". J Cell Biol. 138 (2): 283–90. doi:10.1083/jcb.138.2.283. PMC 2138197. PMID 9230071.

[entrez-6] "Entrez Gene: RABEPK Rab9 effector protein with kelch motifs".

[pmid14530284-7] Ikonomov, Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia (Dec 2003). "Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40". J. Biol. Chem. 278 (51): 50863–71. doi:10.1074/jbc.M307260200. ISSN 0021-9258. PMID 14530284.

RABEPK

Interactions

References

Further reading

External links