RBM19

RBM19

Identifiers

RBM19, RNA binding motif protein 19, Mrd1

External IDs

OMIM: 616444; MGI: 1921361; GeneCards: RBM19

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2DGW

Gene location (Human)

Chr.	Chromosome 12 (human)

Band	12q24.13-q24.21	Start	113,816,738 bp
Band	12q24.13-q24.21	End	113,966,325 bp

Gene location (Mouse)

Chr.	Chromosome 5 (mouse)

Band	5\|5 F	Start	120,254,530 bp
Band	5\|5 F	End	120,337,046 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

sural nerve

left lobe of thyroid gland

right lobe of thyroid gland

right uterine tube

left ovary

apex of heart

right ovary

left adrenal cortex

right adrenal cortex

body of uterus

Top expressed in

yolk sac

tail of embryo

interventricular septum

zygote

genital tubercle

epiblast

spermatocyte

morula

internal carotid artery

embryo

More reference expression data


More reference expression data

Gene ontology
Molecular function	nucleic acid binding RNA binding
Cellular component	cytoplasm nucleolus membrane nucleoplasm chromosome nucleus nuclear speck
Biological process	multicellular organism development positive regulation of embryonic development regulation of alternative mRNA splicing, via spliceosome mRNA cis splicing, via spliceosome
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


9904


74111


ENSG00000122965


ENSMUSG00000029594


Q9Y4C8


Q8R3C6

RefSeq (mRNA)


NM_001146698 NM_001146699 NM_016196


NM_028762

RefSeq (protein)


NP_001140170 NP_001140171 NP_057280


NP_083038

Location (UCSC)

Chr 12: 113.82 – 113.97 Mb

Chr 5: 120.25 – 120.34 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Probable RNA-binding protein 19 is a protein that in humans is encoded by the RBM19 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000122965 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000029594 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Ishikawa K, Nagase T, Suyama M, et al. (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
↑ Wiemann S, Weil B, Wellenreuther R, et al. (Mar 2001). "Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
↑ "Entrez Gene: RBM19 RNA binding motif protein 19".

Further reading

Andersen JS, Lyon CE, Fox AH, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Scherl A, Couté Y, Déon C, et al. (2003). "Functional Proteomic Analysis of Human Nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mayer AN, Fishman MC (2003). "Nil per os encodes a conserved RNA recognition motif protein required for morphogenesis and cytodifferentiation of digestive organs in zebrafish". Development. 130 (17): 3917–28. doi:10.1242/dev.00600. PMID 12874115.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional Proteomics Mapping of a Human Signaling Pathway". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMC 442148. PMID 15231748.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

v t e PDB gallery
2cpf: Solution structure of the penultimate RNA recognition motif of hypothetical RNA-binding protein RBM19 2cph: Solution structure of the C-terminal RNA recognition motif of hypothetical RNA-binding protein RBM19 2dgw: Solution structure of the second RNA recognition motif in RNA-binding protein 19

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