TRNA methyltransferase 10A

TRMT10A
Identifiers
Aliases	TRMT10A, HEL-S-88, RG9MTD2, TRM10, MSSGM, MSSGM1, tRNA methyltransferase 10A
External IDs	OMIM: 616013; MGI: 1920421; GeneCards: TRMT10A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4FMW
Enzyme activity
Gene location (Human)
Chr.	Chromosome 4 (human)
End	99,564,039 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	137,865,582 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; Achilles tendon; ; islet of Langerhans; ; right uterine tube; ; body of pancreas; ; right lobe of liver; ; bronchial epithelial cell; ; mucosa of ileum; ; monocyte;
	Top expressed in
	spermatocyte; ; spermatid; ; seminiferous tubule; ; primitive streak; ; genital tubercle; ; lumbar spinal ganglion; ; tail of embryo; ; otic placode; ; renal corpuscle; ; otic vesicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	methyltransferase activity; transferase activity; tRNA binding; RNA binding; tRNA (guanine-N1-)-methyltransferase activity; tRNA (guanine(9)-N(1))-methyltransferase activity;
Cellular component	nucleolus; extracellular exosome; nucleus; nucleoplasm; cytosol; actin cytoskeleton; mitochondrion;
Biological process	methylation; tRNA methylation; mitochondrial tRNA processing;
	Sources:Amigo / QuickGO
Orthologs
Databases	NCBI: entry; OMA: entry
	93587
	108943
	ENSG00000145331
	ENSMUSG00000004127
	Q8TBZ6
	Q8C1Z8
NM_001134665; NM_001134666; NM_152292; NM_001375880; NM_001375881;
	NM_001375882
	NM_175389; NM_001348196; NM_001348197
NP_001128137; NP_001128138; NP_689505; NP_001362809; NP_001362810;
	NP_001362811
NP_780598; NP_001335125; NP_001335126; NP_001391294; NP_001391297;
	NP_001391298; NP_001391299; NP_001391300; NP_001391301; NP_001391302; NP_001391303; NP_001391304; NP_001391305; NP_001391307; NP_001391308; NP_001391309; NP_001391310; NP_001391311; NP_001391312; NP_001391313; NP_001391314; NP_001391315
	Wikidata
View/Edit Human	View/Edit Mouse

tRNA methyltransferase 10A is an enzyme that in humans is encoded by the TRM10 gene (previously RG9MTD2). As an enzyme it functions as a tRNA (guanine9-N1)-methyltransferase.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000145331 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004127 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
1 2 "RNA (guanine-9-) methyltransferase domain containing 2". Retrieved 2011-12-06.

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[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000145331 – Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000004127 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] 1 2 "RNA (guanine-9-) methyltransferase domain containing 2". Retrieved 2011-12-06.