RHPN1

RHPN1

Identifiers

RHPN1, ODF5, RHOPHILIN, RHPN, rhophilin, Rho GTPase binding protein 1, rhophilin Rho GTPase binding protein 1

External IDs

OMIM: 601031; MGI: 1098783; GeneCards: RHPN1

Gene location (Human)

Chr.	Chromosome 8 (human)

Band	8q24.3	Start	143,368,876 bp
Band	8q24.3	End	143,384,221 bp

Gene location (Mouse)

Chr.	Chromosome 15 (mouse)

Band	15\|15 D3	Start	75,576,129 bp
Band	15\|15 D3	End	75,587,334 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

right lobe of thyroid gland

left lobe of thyroid gland

anterior pituitary

right uterine tube

right frontal lobe

nucleus accumbens

Brodmann area 9

amygdala

cingulate gyrus

anterior cingulate cortex

Top expressed in

saccule

neural layer of retina

spermatocyte

otic vesicle

right kidney

spermatid

otic placode

proximal tubule

renal corpuscle

ventricular zone

More reference expression data


More reference expression data

Gene ontology
Molecular function	protein binding
Cellular component	cytosol
Biological process	signal transduction
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


114822


14787


ENSG00000158106


ENSMUSG00000022580


Q8TCX5


Q61085

RefSeq (mRNA)


NM_052924


NM_001163465 NM_008164

RefSeq (protein)


NP_443156


NP_001156937 NP_032190

Location (UCSC)

Chr 8: 143.37 – 143.38 Mb

Chr 15: 75.58 – 75.59 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Rhophilin-1 is a protein that in humans is encoded by the RHPN1 gene.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000158106 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000022580 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ Nagase T, Kikuno R, Ohara O (Sep 2001). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins". DNA Res. 8 (4): 179–87. doi:10.1093/dnares/8.4.179. PMID 11572484.
↑ "Entrez Gene: RHPN1 rhophilin, Rho GTPase binding protein 1".

Further reading

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Jaffe AB, Aspenström P, Hall A (2004). "Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways". Mol. Cell. Biol. 24 (4): 1736–46. doi:10.1128/MCB.24.4.1736-1746.2004. PMC 344169. PMID 14749388.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Peck JW, Oberst M, Bouker KB, et al. (2003). "The RhoA-binding protein, rhophilin-2, regulates actin cytoskeleton organization". J. Biol. Chem. 277 (46): 43924–32. doi:10.1074/jbc.M203569200. PMID 12221077.
Fujita A, Nakamura K, Kato T, et al. (2000). "Ropporin, a sperm-specific binding protein of rhophilin, that is localized in the fibrous sheath of sperm flagella". J. Cell Sci. 113 (1): 103–12. doi:10.1242/jcs.113.1.103. hdl:2433/181273. PMID 10591629.

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