RRP1B

RRP1B

Identifiers

RRP1B, KIAA0179, NNP1L, Nnp1, PPP1R136, RRP1, ribosomal RNA processing 1B

External IDs

OMIM: 610654; MGI: 1919712; GeneCards: RRP1B

Gene location (Human)

Chr.	Chromosome 21 (human)

Band	21q22.3	Start	43,659,560 bp
Band	21q22.3	End	43,696,079 bp

Gene location (Mouse)

Chr.	Chromosome 17 (mouse)

Band	17\|17 B1	Start	32,255,074 bp
Band	17\|17 B1	End	32,281,839 bp

RNA expression pattern

Human

Mouse (ortholog)

Top expressed in

germinal epithelium

gingival epithelium

visceral pleura

parietal pleura

tibia

retinal pigment epithelium

endothelial cell

tendon of biceps brachii

skin of hip

mucosa of paranasal sinus

Top expressed in

tail of embryo

neural layer of retina

Rostral migratory stream

primitive streak

genital tubercle

epiblast

embryo

morula

embryo

blastocyst

More reference expression data


More reference expression data

Gene ontology
Molecular function	RNA binding transcription coactivator activity protein binding
Cellular component	heterochromatin preribosome, small subunit precursor cytosol euchromatin nucleolus nucleus preribosome, large subunit precursor granular component nucleoplasm chromosome
Biological process	negative regulation of phosphatase activity rRNA processing negative regulation of GTPase activity positive regulation of apoptotic process regulation of RNA splicing positive regulation of transcription by RNA polymerase II cellular response to virus mRNA processing apoptotic process RNA splicing
Sources:Amigo / QuickGO

Databases

NCBI: entry; OMA: entry

Species

Human

Mouse


23076


72462


ENSG00000160208


ENSMUSG00000058392


Q14684


Q91YK2

RefSeq (mRNA)


NM_015056


NM_001163734 NM_028244

RefSeq (protein)


NP_055871


NP_001157206 NP_082520

Location (UCSC)

Chr 21: 43.66 – 43.7 Mb

Chr 17: 32.26 – 32.28 Mb

PubMed search

View/Edit Human

View/Edit Mouse

Ribosomal RNA processing protein 1 homolog B is a protein encoded by RRP1B gene which is located on Chromosome 21.

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000160208 – Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000058392 – Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: KIAA0179 KIAA0179".

Further reading

Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Hu YH, Warnatz HJ, Vanhecke D, Wagner F, Fiebitz A, Thamm S, Kahlem P, Lehrach H, Yaspo ML, Janitz M (June 2006). "Cell array-based intracellular localization screening reveals novel functional features of human chromosome 21 proteins". BMC Genomics. 7 155. doi:10.1186/1471-2164-7-155. PMC 1526728. PMID 16780588.
Nousiainen M, Silljé HH, Sauer G, Nigg EA, Körner R (April 2006). "Phosphoproteome analysis of the human mitotic spindle". Proceedings of the National Academy of Sciences of the United States of America. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.
Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M (January 2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413. S2CID 4344740.
Lehner B, Sanderson CM (July 2004). "A protein interaction framework for human mRNA degradation". Genome Research. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
Scherl A, Couté Y, Déon C, Callé A, Kindbeiter K, Sanchez JC, Greco A, Hochstrasser D, Diaz JJ (November 2002). "Functional proteomic analysis of human nucleolus". Molecular Biology of the Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, Mann M, Lamond AI (January 2002). "Directed proteomic analysis of the human nucleolus". Current Biology. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Nagase T, Seki N, Ishikawa K, Tanaka A, Nomura N (February 1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.

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